FBXW8 Produkte
(F-Box and WD Repeat Domain Containing 8 (FBXW8))
Kategorien
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.
Ausgewählte FBXW8 Kategorien
FBXW8 Antikörper
High quality antibodies with extensive validation data.
FBXW8 ELISA Kits
Reliable ELISA kits for a wide range of species.
FBXW8 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FBXW8 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, FACS, IHC (p)
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN654676
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
- (2)
Kat. Nr.
ABIN565252
Menge
50 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p), EIA
Validierungen
- (4)
Kat. Nr.
ABIN952296
Menge
0.4 mL
Datenblatt
Datenblatt
Empfohlene FBXW8 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1743139
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Sheep
Analytical Method
Validierungen
Kat. Nr.
ABIN1774044
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Dog
Analytical Method
Validierungen
Kat. Nr.
ABIN1769148
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FBXW8 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1353881
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3092555
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3136178
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FBXW8 Produkten
: "Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated." in: PLoS ONE, Vol. 10, Issue 3, pp. e0121089, (2015) (PubMed).: "The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1." in: The Journal of biological chemistry, Vol. 289, Issue 7, pp. 4009-17, (2014) (PubMed).
: "Effect of ursolic acid on MAPK in cyclin D1 signaling and RING-type E3 ligase (SCF E3s) in two endometrial cancer cell lines." in: Nutrition and cancer, Vol. 65, Issue 7, pp. 1026-33, (2013) (PubMed).
: "Cullin 7 and Fbxw 8 expression in trophoblastic cells is regulated via oxygen tension: implications for intrauterine growth restriction?" in: The journal of maternal-fetal & neonatal medicine, Vol. 25, Issue 11, pp. 2209-15, (2012) (PubMed).
: "Fbxw8 is involved in the proliferation of human choriocarcinoma JEG-3 cells." in: Molecular biology reports, Vol. 38, Issue 3, pp. 1741-7, (2011) (PubMed).
: "A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells." in: The Journal of biological chemistry, Vol. 283, Issue 39, pp. 26759-70, (2008) (PubMed).
Synonyme und alternative Namen zu FBXW8
F-box and WD repeat domain containing 8 (FBXW8), F-box and WD repeat domain containing 8 (Fbxw8), ring finger protein, transmembrane 2 (RNFT2), F-box and WD-40 domain protein 8 (Fbxw8), 4930438M06Rik, FBW6, FBW8, FBX29, Fbx29, FBXO29, FBXW6Bezeichner auf Proteinebene für FBXW8
- F-box and WD-40 domain protein 8
- F-box and WD-40 domain-containing protein 8
- F-box only protein 29
- F-box/WD repeat-containing protein 8
- F-box protein FBX29
Sie sind hier:
