Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
Spezifität
Reacts with human Fibroblast Growth Factor Receptor 1 beta (FGFR1β). Epitope is undetermined but presumed to be near junction of the common FGFr1 NH2-terminus and NH2-terminus of Ig loop II.
Aufreinigung
Purified (protein G)
Immunogen
Recombinant human ectodomain of FGFr1beta expressed in E. coli beginning with pro23, antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH-terminal glu-phe sequences.
Klon
M17A3
Isotyp
IgG2b
Applikationshinweise
Working dilution: Optimal dilution should be determined by the end user. The following are guidelines only : WB(1 μg/mL)
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS, pH 7.4.
Handhabung
Dilute in PBS or medium that is identical to that used in the assay system.
Lagerung
-20 °C/-80 °C
Informationen zur Lagerung
Stable for at least one year at -20°C to -70°C. Avoid multiple freeze-thaw cycles.
Fibroblast Growth Factor Receptor 1 (FGFR1) is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. This protein is a Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration.