FGFR2 Produkte
(Fibroblast Growth Factor Receptor 2 (FGFR2))
Kategorien
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009].
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Ausgewählte FGFR2 Kategorien
FGFR2 Antikörper
High quality antibodies with extensive validation data.
FGFR2 ELISA Kits
Reliable ELISA kits for a wide range of species.
FGFR2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FGFR2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, FACS, IF, IHC (p)
Validierungen
- (5)
- (7)
Kat. Nr.
ABIN391965
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC
Validierungen
- (7)
Kat. Nr.
ABIN3022855
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, IF, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN391968
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene FGFR2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955878
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381135
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6730491
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FGFR2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354041
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354039
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Mammalian Cells
Validierungen
- (1)
Kat. Nr.
ABIN7538234
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FGFR2 Produkten
: "Leucocyte and Platelet-rich Fibrin: a carrier of autologous multipotent cells for regenerative medicine." in: Journal of cellular and molecular medicine, Vol. 22, Issue 3, pp. 1840-1854, (2018) (PubMed).: "Identification and validation of FGFR2 peptide for detection of early Barrett's neoplasia." in: Oncotarget, Vol. 8, Issue 50, pp. 87095-87106, (2017) (PubMed).
: "Interactions between FGFR2 and RSK2-implications for breast cancer prognosis." in: Tumour biology, Vol. 37, Issue 10, pp. 13721-13731, (2016) (PubMed).
: "miR-223 Regulates Adipogenic and Osteogenic Differentiation of Mesenchymal Stem Cells Through a C/EBPs/miR-223/FGFR2 Regulatory Feedback Loop." in: Stem cells (Dayton, Ohio), Vol. 33, Issue 5, pp. 1589-600, (2015) (PubMed).
: "Upregulation of ANGPTL4 messenger RNA and protein in severely calcified carotid plaques." in: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 23, Issue 5, pp. 933-47, (2014) (PubMed).
: "Low prognostic implication of fibroblast growth factor family activation in triple-negative breast cancer subsets." in: Annals of surgical oncology, Vol. 21, Issue 5, pp. 1561-8, (2014) (PubMed).
: "Mannose phosphate isomerase regulates fibroblast growth factor receptor family signaling and glioma radiosensitivity." in: PLoS ONE, Vol. 9, Issue 10, pp. e110345, (2014) (PubMed).
: "Epithelial-mesenchymal transition confers resistance to selective FGFR inhibitors in SNU-16 gastric cancer cells." in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, (2014) (PubMed).
: "Kinase domain activation of FGFR2 yields high-grade lung adenocarcinoma sensitive to a Pan-FGFR inhibitor in a mouse model of NSCLC." in: Cancer research, Vol. 74, Issue 17, pp. 4676-84, (2014) (PubMed).
: "The expression of fibroblast growth factor receptors during early bovine conceptus development and pharmacological analysis of their actions on trophoblast growth in vitro." in: Reproduction (Cambridge, England), Vol. 145, Issue 2, pp. 191-201, (2013) (PubMed).
Synonyme und alternative Namen zu FGFR2
fibroblast growth factor receptor 2 (FGFR2), fibroblast growth factor receptor 2 (LOC100084641), fibroblast growth factor receptor 2 (fgfr2), fibroblast growth factor receptor 2 (Fgfr2), fibroblast growth factor receptor 2 L homeolog (fgfr2.L), AU043015, AW556123, BBDS, bek, BEK, Bek, bfr-1, BFR-1, cd332, CD332, cek3, CEK3, cfd1, CFD1, DKFZp469H1521, ect1, ECT1, fc56c05, FGF-R, FGFR, fgfr-2, Fgfr-2, Fgfr-7, FGFR2, FGFR2IIIb, Fgfr7, fgfr72IIIb, jws, JWS, k-sam, K-SAM, kgfr, KGFR, KGFRTr, svs, tk14, TK14, tk25, TK25, wu:fc56c05, xfgfr2Bezeichner auf Proteinebene für FGFR2
- fibroblast growth factor receptor 2
- bacteria-expressed kinase
- keratinocyte growth factor receptor
- fibroblast growth factor receptor 2 IIIb
- fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome)
- BEK fibroblast growth factor receptor
- FGF receptor
- FGFR-2
- hydroxyaryl-protein kinase
- protein tyrosine kinase, receptor like 14
- soluble FGFR4 variant 4
- FGF-7 receptor 2IIIb
- fgf receptor
- chicken tyrosine kinase (cek3)
- receptor tyrosine kinase
- tyrosine kinase receptor CEK3
- fibroblast growth factor receptor-2
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