Fgr Produkte
(Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
Kategorien
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
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Ausgewählte Fgr Kategorien
Fgr Antikörper
High quality antibodies with extensive validation data.
Fgr ELISA Kits
Reliable ELISA kits for a wide range of species.
Fgr Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Fgr Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), IF
Validierungen
- (2)
- (5)
Kat. Nr.
ABIN392096
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p)
Validierungen
- (6)
Kat. Nr.
ABIN560883
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7174020
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene Fgr ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4886105
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4882882
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6385940
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Fgr Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354064
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354066
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN2721125
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Fgr Produkten
: "Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells." in: eLife, Vol. 8, (2020) (PubMed).: "Src family kinase expression and subcellular localization in macrophages: implications for their role in CSF-1-induced macrophage migration." in: Journal of leukocyte biology, Vol. 100, Issue 1, pp. 163-75, (2016) (PubMed).
: "LynA regulates an inflammation-sensitive signaling checkpoint in macrophages." in: eLife, Vol. 4, (2016) (PubMed).
: "High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells." in: Molecular cancer research : MCR, Vol. 9, Issue 6, pp. 724-32, (2011) (PubMed).
: "SRC family kinase activity is up-regulated in hormone-refractory prostate cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 10, pp. 3540-9, (2009) (PubMed).
: "Coactivator assembly at the promoter: efficient recruitment of SRC2 is coupled to cooperative DNA binding by the progesterone receptor." in: Biochemistry, Vol. 46, Issue 39, pp. 11023-32, (2007) (PubMed).
: "The Src family kinases Hck and Fgr negatively regulate neutrophil and dendritic cell chemokine signaling via PIR-B." in: Immunity, Vol. 22, Issue 2, pp. 235-46, (2005) (PubMed).
: "Inhibition of receptor-dependent urokinase signaling by specific Ser to Glu substitutions." in: Biological chemistry, Vol. 383, Issue 1, pp. 107-13, (2002) (PubMed).
: "Expression of the retinoblastoma protein is regulated in normal human tissues." in: The American journal of pathology, Vol. 144, Issue 3, pp. 500-10, (1994) (PubMed).
: "The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest." in: Cell, Vol. 79, Issue 1, pp. 119-30, (1994) (PubMed).
Synonyme und alternative Namen zu Fgr
FGR proto-oncogene, Src family tyrosine kinase (FGR), FGR proto-oncogene, Src family tyrosine kinase (Fgr), c-fgr, c-src2, p55-Fgr, p55c-fgr, p58-Fgr, p58c-fgr, SRC2Bezeichner auf Proteinebene für Fgr
- Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
- c-fgr protooncogene
- c-src-2 proto-oncogene
- p55-c-fgr protein
- proto-oncogene c-Fgr
- proto-oncogene tyrosine-protein kinase FGR
- tyrosine-protein kinase Fgr
- v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog
- Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog
- proto-oncogene tyrosine-protein kinase Fgr
- tyrosine-protein kinase Fgr-like
- p55-Fgr
- feline Gardner-Rasheed sarcoma viral oncogene homolog
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