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FHL1 Produkte

(Four and A Half LIM Domains 1 (FHL1))

Kategorien

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.[provided by RefSeq, Nov 2009].

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Ausgewählte FHL1 Kategorien

FHL1 Antikörper

High quality antibodies with extensive validation data.

FHL1 ELISA Kits

Reliable ELISA kits for a wide range of species.

FHL1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FHL1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN560899
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IF, IC
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN7306298
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
Applikation WB, IHC
Validierungen
  • (12)
  • (4)
Kat. Nr. ABIN2775759
Menge 100 μL
Datenblatt Datenblatt

Empfohlene FHL1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955987
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4882885
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1133659
Menge 96 tests
Datenblatt Datenblatt

Empfohlene FHL1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1354072
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1354074
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN2721133
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FHL1 Produkten

Meertens, Hafirassou, Couderc, Bonnet-Madin, Kril, Kümmerer, Labeau, Brugier, Simon-Loriere, Burlaud-Gaillard, Doyen, Pezzi, Goupil, Rafasse, Vidalain, Bertrand-Legout, Gueneau, Juntas-Morales et al.: "FHL1 is a major host factor for chikungunya virus infection. ..." in: Nature, Vol. 574, Issue 7777, pp. 259-263, (2019) (PubMed).

Le Thanh, Meinke, Korfali, Srsen, Robson, Wehnert, Schoser, Sewry, Schirmer: "Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology." in: Neuromuscular disorders : NMD, Vol. 27, Issue 4, pp. 338-351, (2017) (PubMed).

Xue, Schoser, Rao, Quadrelli, Vaglio, Rupp, Beichler, Nelson, Schapacher-Tilp, Windpassinger, Wilcox: "Exome Sequencing Identified a Splice Site Mutation in FHL1 that Causes Uruguay Syndrome, an X-Linked Disorder With Skeletal Muscle Hypertrophy and Premature Cardiac Death." in: Circulation. Cardiovascular genetics, Vol. 9, Issue 2, pp. 130-5, (2016) (PubMed).

Emmanuele, Kubota, Garcia-Diaz, Garone, Akman, Sánchez-Gutiérrez, Escudero, Kariya, Homma, Tanji, Quinzii, Hirano: "Fhl1 W122S causes loss of protein function and late-onset mild myopathy." in: Human molecular genetics, Vol. 24, Issue 3, pp. 714-26, (2015) (PubMed).

Albrecht, Wick, Hallgren, Tjärnlund, Nagaraju, Andrade, Thompson, Coley, Phadke, Diaz-Gallo, Bottai, Nennesmo, Chemin, Herrath, Johansson, Wikberg, Ytterberg, Zubarev, Danielsson, Krystufkova et al.: "Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies. ..." in: The Journal of clinical investigation, Vol. 125, Issue 12, pp. 4612-24, (2015) (PubMed).

Ma, Mao, Shen, Zheng, Li, Liu, Ni: "Atractylenolide I-mediated Notch pathway inhibition attenuates gastric cancer stem cell traits." in: Biochemical and biophysical research communications, Vol. 450, Issue 1, pp. 353-9, (2014) (PubMed).

Zhang, Chen, Sharma, Moon, Sheftel, Dawood, Nghiem, Wu, Li, Gramolini, Sorensen, Penninger, Brumell, Liu: "HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress." in: Nature communications, Vol. 5, pp. 3430, (2014) (PubMed).

Fujii, Hayashi, Kawamura, Higuchi, Tsugawa, Ohyagi, Hayashi, Nishino, Kira: "A case of adult-onset reducing body myopathy presenting a novel clinical feature, asymmetrical involvement of the sternocleidomastoid and trapezius muscles." in: Journal of the neurological sciences, Vol. 343, Issue 1-2, pp. 206-10, (2014) (PubMed).

Koike, Kasamatsu, Iyoda, Saito, Kouzu, Koike, Sakamoto, Ogawara, Tanzawa, Uzawa: "High prevalence of epigenetic inactivation of the human four and a half LIM domains 1 gene in human oral cancer." in: International journal of oncology, Vol. 42, Issue 1, pp. 141-50, (2012) (PubMed).

Sharma, Shathasivam, Ignatchenko, Kislinger, Gramolini: "Identification of an FHL1 protein complex containing ACTN1, ACTN4, and PDLIM1 using affinity purifications and MS-based protein-protein interaction analysis." in: Molecular bioSystems, Vol. 7, Issue 4, pp. 1185-96, (2011) (PubMed).

Synonyme und alternative Namen zu FHL1

four and a half LIM domains 1 (fhl1), four and a half LIM domains 1 (FHL1), four and a half LIM domains 1a (fhl1a), Four and a half LIM domains protein 1 (fhl1), four and a half LIM domains 1 S homeolog (fhl1.S), four and a half LIM domains 1 (Fhl1), DKFZp468O1927, fhl, FHL-1, fhl1, FHL1, Fhl1, FHL1A, FHL1B, fhla, FLH1A, KYOT, KyoT, MGC89165, SLIM, SLIM-1, SLIM1, SLIMMER, XMPMA, zgc:92025

Bezeichner auf Proteinebene für FHL1

  • four and a half LIM domains 1
  • four and a half LIM domains protein 1-like
  • four and a half LIM domains a
  • four and a half LIM domains protein 1
  • Four and a half LIM domains protein 1
  • four and a half lim domains protein 1
  • LIM protein SLIMMER
  • four-and-a-half Lin11, Isl-1 and Mec-3 domains 1
  • skeletal muscle LIM-protein 1
  • FHL-1
  • RAM14-1
  • RBP-associated molecule 14-1
  • SLIM
  • SLIM-1
  • four and a half LIM domains 1 protein
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