Fibroblast Growth Factor Receptor Produkte
(Fibroblast Growth Factor Receptor (FGFR))
Kategorien
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol- 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by ubiquitination, internalization and degradation (By similarity).
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Ausgewählte Fibroblast Growth Factor Receptor Kategorien
Fibroblast Growth Factor Receptor Antikörper
High quality antibodies with extensive validation data.
Fibroblast Growth Factor Receptor ELISA Kits
Reliable ELISA kits for a wide range of species.
Empfohlene Fibroblast Growth Factor Receptor Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
Kat. Nr.
ABIN2267319
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
Kat. Nr.
ABIN2267321
Menge
1 mg
Datenblatt
Datenblatt
Empfohlene Fibroblast Growth Factor Receptor ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Pig
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN778747
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Goat
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN989383
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Cow
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN989385
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Fibroblast Growth Factor Receptor Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Sea Squirt
Source
Yeast
Validierungen
Kat. Nr.
ABIN1628579
Menge
1 mg
Datenblatt
Datenblatt
Synonyme und alternative Namen zu Fibroblast Growth Factor Receptor
heartless (htl), fibroblast growth factor receptor 1 L homeolog (fgfr1.L), fibroblast growth factor receptor (FGFR), fibroblast growth factor receptor 1 S homeolog (fgfr1.S), fibroblast growth factor receptor (fgfr), fibroblast growth factor receptor 1 (FGFR1), fibroblast growth factor receptor 1 (fgfr1), fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog (fgfr3.L), basic fibroblast growth factor receptor 1 (CpipJ_CPIJ005849), ach, bfgfr, cd331, cd333, cek, cek2, CG7223, CT22273, CT39172, DFGF-R1, DFGF-R2, DFR-1, Dfr-1, DFR1, Dfr1, DFR1/DFGF-R2, Dmel\\CG7223, DmHD-38, DPR3, Dtk1, dtk1, DTRK(FR1), EMS2, FGF-R2, fgfbr, FGFR, fgfr, fgfr-1, fgfr-3, fgfr1, FGFR2, flg, FLG-1, flt-2, flt2, FR1, Fr1, hbgfr, HD-38, hsfgfr3ex, Htl, HTL/FGFR1, i79, i100, i150, j372, jtk4, kal2, n-sam, ogd, Tk1, x1fgfr, X1FGFR, XFGFR-1, xfgfr1, XFGFRA2Bezeichner auf Proteinebene für Fibroblast Growth Factor Receptor
- CG7223-PA
- CG7223-PB
- CG7223-PC
- FGF receptor
- fibroblast growth factor receptor
- fibroblast growth factor receptor 1
- htl-PA
- htl-PB
- htl-PC
- FGFR-1
- fibroblast growth factor receptor-1
- fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
- ibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
- basic fibroblast growth factor receptor 1
- basic fibroblast growth factor receptor 1-like
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