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Fibulin 5 Produkte

(Fibulin 5 (FBLN5))
The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008].

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Ausgewählte Fibulin 5 Kategorien

Fibulin 5 Antikörper

High quality antibodies with extensive validation data.

Fibulin 5 ELISA Kits

Reliable ELISA kits for a wide range of species.

Fibulin 5 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Fibulin 5 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC (p)
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN728473
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (3)
Kat. Nr. ABIN7438958
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC
Validierungen
  • (3)
  • (2)
Kat. Nr. ABIN969131
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Fibulin 5 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6955903
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966819
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966820
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Fibulin 5 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN2752787
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN2721183
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7404167
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Fibulin 5 Produkten

Sun, Tomita, Salinger, Tilvawala, Li, Hakami, Liu, Tsoyi, Rosas, Reinhardt, Thompson, Ho: "PAD2-mediated citrullination of Fibulin-5 promotes elastogenesis." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 102, pp. 70-84, (2022) (PubMed).

Dekker, van Geemen, van den Bogaerdt, Driessen-Mol, Aikawa, Smits: "Sheep-Specific Immunohistochemical Panel for the Evaluation of Regenerative and Inflammatory Processes in Tissue-Engineered Heart Valves." in: Frontiers in cardiovascular medicine, Vol. 5, pp. 105, (2018) (PubMed).

Hu, Dong, Zhao, Xu, Qin: "Fibulin-5: a novel biomarker for evaluating severity and predicting prognosis in patients with acute intracerebral haemorrhage." in: European journal of neurology, Vol. 23, Issue 7, pp. 1195-201, (2016) (PubMed).

Guo, Cheng, Chen, Xing, Xu, Feng, Qin: "Overexpression of Fibulin-5 Attenuates Ischemia/Reperfusion Injury After Middle Cerebral Artery Occlusion in Rats." in: Molecular neurobiology, (2015) (PubMed).

Sideek, Menz, Parsi, Gibson: "LTBP-2 competes with tropoelastin for binding to fibulin-5 and heparin, and is a negative modulator of elastinogenesis." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 34, pp. 114-23, (2014) (PubMed).

Albig, Neil, Schiemann: "Fibulins 3 and 5 antagonize tumor angiogenesis in vivo." in: Cancer research, Vol. 66, Issue 5, pp. 2621-9, (2006) (PubMed).

Wen, Hochholdinger, Sauer, Bruce, Schnable: "The roothairless1 gene of maize encodes a homolog of sec3, which is involved in polar exocytosis." in: Plant physiology, Vol. 138, Issue 3, pp. 1637-43, (2005) (PubMed).

Kadoya, Sasaki, Kostka, Timpl, Matsuzaki, Kumagai, Sakai, Nishiyama, Amano: "Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis." in: The British journal of dermatology, Vol. 153, Issue 3, pp. 607-12, (2005) (PubMed).

Wang, LeMaire, Chen, Carter, Shen, Gan, Bartsch, Wilks, Utama, Ou, Thompson, Coselli, Wang: "Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection." in: Surgery, Vol. 138, Issue 2, pp. 352-9, (2005) (PubMed).

Synonyme und alternative Namen zu Fibulin 5

fibulin 5 (fbln5), fibulin 5 (FBLN5), fibulin 5 (Fbln5), A55, ADCL2, ARCL1A, ARMD3, DANCE, DKFZp469K0327, EVEC, FBLN5, FIBL-5, Fibulin-5, MGC108414, UP50, zgc:103575

Bezeichner auf Proteinebene für Fibulin 5

  • fibulin-5
  • fibulin 5
  • fibulin-5-like
  • developmental arteries and neural crest EGF-like protein
  • urine p50 protein
  • FIBL-5
  • EVEC
  • dance
  • embryonic vascular EGF repeat-containing protein
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