Filamin A Produkte
(Filamin A, alpha (FLNA))
Kategorien
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009].
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Ausgewählte Filamin A Kategorien
Filamin A Antikörper
High quality antibodies with extensive validation data.
Filamin A ELISA Kits
Reliable ELISA kits for a wide range of species.
Filamin A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Filamin A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7440788
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, IF
Validierungen
- (6)
Kat. Nr.
ABIN7259092
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), PLA
Validierungen
- (8)
- (5)
Kat. Nr.
ABIN560922
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene Filamin A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955914
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381139
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN512498
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Filamin A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354202
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN2721188
Menge
20 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7412995
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Filamin A Produkten
: "DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk." in: eLife, Vol. 5, (2016) (PubMed).: "Filamin A (FLNA) modulates chemosensitivity to docetaxel in triple-negative breast cancer through the MAPK/ERK pathway." in: Tumour biology, Vol. 37, Issue 4, pp. 5107-15, (2016) (PubMed).
: "Filamin A is reduced and contributes to the CASR sensitivity in human parathyroid tumors." in: Journal of molecular endocrinology, Vol. 58, Issue 2, pp. 91-103, (2016) (PubMed).
: "Familial periventricular nodular heterotopia, epilepsy and Melnick-Needles Syndrome caused by a single FLNA mutation with combined gain-of-function and loss-of-function effects." in: Journal of medical genetics, Vol. 52, Issue 6, pp. 405-12, (2015) (PubMed).
: "Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0119686, (2015) (PubMed).
: "Filamin A Expression Negatively Regulates Sphingosine-1-Phosphate-Induced NF-?B Activation in Melanoma Cells by Inhibition of Akt Signaling." in: Molecular and cellular biology, (2015) (PubMed).
: "S6K is a morphogenic protein with a mechanism involving Filamin-A phosphorylation and phosphatidic acid binding." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 4, pp. 1299-313, (2015) (PubMed).
: "Filamin A (FLNA) plays an essential role in somatostatin receptor 2 (SST2) signaling and stabilization after agonist stimulation in human and rat somatotroph tumor cells." in: Endocrinology, Vol. 155, Issue 8, pp. 2932-41, (2014) (PubMed).
: "Novel no-stop FLNA mutation causes multi-organ involvement in males." in: American journal of medical genetics. Part A, Vol. 161A, Issue 9, pp. 2376-84, (2013) (PubMed).
: "Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 18, Issue 9, pp. 810-22, (2013) (PubMed).
Synonyme und alternative Namen zu Filamin A
filamin A (FLNA), filamin A, alpha (actin binding protein 280) (flna), filamin, alpha (Flna), filamin A (Flna), filamin-A (LOC587317), filamin A (flna), cheerio (cher), filamin-A (LOC100380643), ABP-280, ABPX, CG3937, Cher, CSBS, CVD1, Dilp2, Dmel\\CG3937, F730004A14Rik, fb98b06, Fil, filamin-1, FLN, FLN-A, FLN1, Fln1, FMD, joy, MGC147094, MNS, NHBP, OPD, OPD1, OPD2, RGD1560614, sko, wu:fb98b06, wu:fd09g03, wu:fd49a06, XLVD, XMVDBezeichner auf Proteinebene für Filamin A
- actin binding protein 280
- alpha-filamin
- endothelial actin-binding protein
- filamin-1
- filamin-A
- non-muscle filamin
- filamin A, alpha (actin binding protein 280)
- fd09g03
- FLN-A
- GENA 379
- actin-binding protein 280
- dilated pupils 2
- filamin A
- Endothelial actin-binding protein 280)
- filamin, alpha
- filamin A, alpha
- CG3937-PA
- CG3937-PB
- CG3937-PF
- CG3937-PG
- CG3937-PH
- CG3937-PI
- CG3937-PK
- CG3937-PL
- CG3937-PM
- CG3937-PN
- Filamin-1
- Filamin-A
- cher-PA
- cher-PB
- cher-PF
- cher-PG
- cher-PH
- cher-PI
- cher-PK
- cher-PL
- cher-PM
- cher-PN
- filamin
- filamin B
- filamin isoform B
- filamin-240
- shi kong
- 450 kDa protein
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