FK506 Binding Protein 1A, 12kDa Produkte
(FK506 Binding Protein 1A, 12kDa (FKBP1A))
Kategorien
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008].
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Ausgewählte FK506 Binding Protein 1A, 12kDa Kategorien
FK506 Binding Protein 1A, 12kDa Antikörper
High quality antibodies with extensive validation data.
FK506 Binding Protein 1A, 12kDa ELISA Kits
Reliable ELISA kits for a wide range of species.
FK506 Binding Protein 1A, 12kDa Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FK506 Binding Protein 1A, 12kDa Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, IHC (p)
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN1882082
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN560904
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (5)
Kat. Nr.
ABIN3022504
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene FK506 Binding Protein 1A, 12kDa ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955918
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955919
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6951130
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FK506 Binding Protein 1A, 12kDa Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN1354116
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122973
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122972
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FK506 Binding Protein 1A, 12kDa Produkten
: "Impact of hypoxia, simulated ischemia and reperfusion in HL-1 cells on the expression of FKBP12/FKBP12.6 and intracellular calcium dynamics." in: Biochemical and biophysical research communications, Vol. 422, Issue 4, pp. 732-8, (2012) (PubMed).: "Immunophilin-loaded erythrocytes as a new delivery strategy for immunosuppressive drugs." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 154, Issue 3, pp. 306-13, (2011) (PubMed).
: "Protein-protein interactions: an application of Tus-Ter mediated protein microarray system." in: Methods in molecular biology (Clifton, N.J.), Vol. 723, pp. 185-200, (2011) (PubMed).
: "Coupling surface plasmon resonance to mass spectrometry to discover novel protein-protein interactions." in: Nature protocols, Vol. 4, Issue 7, pp. 1023-37, (2009) (PubMed).
: "FK506 binding protein 12 differentially accelerates fibril formation of wild type alpha-synuclein and its clinical mutants A30P or A53T." in: Journal of neurochemistry, Vol. 106, Issue 1, pp. 121-33, (2008) (PubMed).
: "A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis." in: Cancer research, Vol. 68, Issue 8, pp. 2934-43, (2008) (PubMed).
: "Increased striatal mRNA and protein levels of the immunophilin FKBP-12 in experimental Parkinson's disease and identification of FKBP-12-binding proteins." in: Journal of proteome research, Vol. 6, Issue 10, pp. 3952-61, (2007) (PubMed).
: "Mechanism of TGFbeta receptor inhibition by FKBP12." in: The EMBO journal, Vol. 16, Issue 13, pp. 3866-76, (1997) (PubMed).
: "Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12." in: Science (New York, N.Y.), Vol. 265, Issue 5172, pp. 674-6, (1994) (PubMed).
: "Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A." in: Nature, Vol. 352, Issue 6338, pp. 803-7, (1991) (PubMed).
Synonyme und alternative Namen zu FK506 Binding Protein 1A, 12kDa
FK506 binding protein 1a (Fkbp1a), FK506 binding protein 1A (FKBP1A), FK506-binding protein (Fkbp12), FK506-binding protein 12 (FKBP12), FK506 binding protein 1Aa (fkbp1aa), FK506 binding protein 1C (FKBP1C), FK506-binding protein (EHI_180160), FK506-binding protein 59 (LOC5573443), FK506-binding protein (Fkbp13), FK506 binding protein like (FKBPL), FK506 binding protein 1A L homeolog (fkbp1a.L), FK506 binding protein 1A (Fkbp1a), FK506 binding protein 1Ab (fkbp1ab), 12kDa, ARABIDOPSIS THALIANA FK506-BINDING PROTEIN 12, ATFKBP12, Bmfkbp13, fj02g10, FK506-binding protein 12, Fkbp, FKBP-1A, FKBP-12, Fkbp1, FKBP1, FKBP1A, FKBP1B, Fkbp2, FKBP12, Fkbp12, FKBP12-T1, FKBP12-T2, IMMUNOPHILIN, mFKBP1, mFKBP12, MSJ1.19, MSJ1_19, PKC12, PKCI2, PPIASE, Rotamase, wu:fj02g10, zgc:73373, zgc:103752Bezeichner auf Proteinebene für FK506 Binding Protein 1A, 12kDa
- 12 kDa FK506-binding protein
- 12 kDa FKBP
- FK506 Binding Protein12-T1
- FK506 binding protein12
- FK506 binding protein12-T2
- FK506-binding protein 1A
- FKBP-12
- FKBP-1A
- FKBP12-Exip3
- PPIase FKBP1A
- calstabin-1
- immunophilin FKBP12
- peptidyl-prolyl cis-trans isomerase FKBP1A
- rotamase
- Immunophilin FKBP12
- binding protein
- FK506-binding protein
- FK506-binding protein 1
- FK506-binding protein 12
- FK506-binding protein 1A (12kD)
- FK506-binding protein, T-cell, 12-kD
- calstabin 1
- protein kinase C inhibitor 2
- FK506 binding protein 1B, 12.6 kDa
- FK506 binding protein 2 (13 kDa)
- FK506-binding protein 1 (12kD)
- FK506-binding protein 1a
- FK506 binding protein 1A, 12kDa
- fk506-binding protein
- FK506-binding protein-like
- FK 506-binding protein
- FK506 binding protein 1-like
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