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FLNC Produkte

(Filamin C, gamma (FLNC))
This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte FLNC Kategorien

FLNC Antikörper

High quality antibodies with extensive validation data.

FLNC ELISA Kits

Reliable ELISA kits for a wide range of species.

FLNC Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FLNC Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7441958
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (2)
  • (2)
Kat. Nr. ABIN560923
Menge 50 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (2)
Kat. Nr. ABIN7435937
Menge 100 μL
Datenblatt Datenblatt

Empfohlene FLNC ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6955916
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Guinea Pig
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN776808
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rabbit
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN774853
Menge 96 tests
Datenblatt Datenblatt

Empfohlene FLNC Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1354206
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7505105
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7413877
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FLNC Produkten

Kiselev, Vaz, Knyazeva, Khudiakov, Tarnovskaya, Liu, Sergushichev, Kazakov, Frishman, Smolina, Pervunina, Jorholt, Sjoberg, Vershinina, Rudenko, Arner, Sejersen, Lindstrand, Kostareva: "De novo mutations in FLNC leading to early-onset restrictive cardiomyopathy and congenital myopathy." in: Human mutation, Vol. 39, Issue 9, pp. 1161-1172, (2018) (PubMed).

Reinstein, Gutierrez-Fernandez, Tzur, Bormans, Marcu, Tayeb-Fligelman, Vinkler, Raas-Rothschild, Irge, Landau, Shohat, Puente, Behar, Lopez-Otın: "Congenital dilated cardiomyopathy caused by biallelic mutations in Filamin C." in: European journal of human genetics : EJHG, Vol. 24, Issue 12, pp. 1792-1796, (2016) (PubMed).

Begay, Tharp, Martin, Graw, Sinagra, Miani, Sweet, Slavov, Stafford, Zeller, Alnefaie, Rowland, Brun, Jones, Gowan, Mestroni, Garrity, Taylor: "FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy." in: JACC. Basic to translational science, Vol. 1, Issue 5, pp. 344-359, (2016) (PubMed).

Valdés-Mas, Gutiérrez-Fernández, Gómez, Coto, Astudillo, Puente, Reguero, Álvarez, Morís, León, Martín, Puente, López-Otín: "Mutations in filamin C cause a new form of familial hypertrophic cardiomyopathy." in: Nature communications, Vol. 5, pp. 5326, (2014) (PubMed).

Kentsis, Shulman, Ahmed, Brennan, Monuteaux, Lee, Lipsett, Paulo, Dedeoglu, Fuhlbrigge, Bachur, Bradwin, Arditi, Sundel, Newburger, Steen, Kim: "Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease." in: EMBO molecular medicine, Vol. 5, Issue 2, pp. 210-20, (2013) (PubMed).

Sakane, Alamir Mahmoud Abdallah, Nakano, Honda, Kitamura, Imoto, Matsushita, Sasaki: "Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 18, Issue 9, pp. 810-22, (2013) (PubMed).

Tsuchiya, Iseda, Hino: "Identification of a novel protein (VBP-1) binding to the von Hippel-Lindau (VHL) tumor suppressor gene product." in: Cancer research, Vol. 56, Issue 13, pp. 2881-5, (1996) (PubMed).

Sharma, Ezzell, Arnaout: "Direct interaction of filamin (ABP-280) with the beta 2-integrin subunit CD18." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 7, pp. 3461-70, (1995) (PubMed).

Price, Caprette, Gomer: "Different temporal patterns of expression result in the same type, amount, and distribution of filamin (ABP) in cardiac and skeletal myofibrils." in: Cell motility and the cytoskeleton, Vol. 27, Issue 3, pp. 248-61, (1994) (PubMed).

Patrosso, Repetto, Villa, Milanesi, Frattini, Faranda, Mancini, Maestrini, Toniolo, Vezzoni: "The exon-intron organization of the human X-linked gene (FLN1) encoding actin-binding protein 280." in: Genomics, Vol. 21, Issue 1, pp. 71-6, (1994) (PubMed).

Synonyme und alternative Namen zu FLNC

filamin C (FLNC), filamin C L homeolog (flnc.L), filamin C (flnc), filamin C, gamma (Flnc), filamin C (Flnc), 1110055E19Rik, ABP-280, ABP280A, ABPA, ABPL, Fln2, FLN2, MFM5, MPD4

Bezeichner auf Proteinebene für FLNC

  • filamin C, gamma (actin binding protein 280)
  • gamma filamin
  • filamin C, gamma
  • filamin-C-like
  • ABP-280-like protein
  • ABP-L
  • FLN-C
  • actin binding protein 280
  • actin-binding protein 280
  • actin-binding-like protein
  • filamin, gamma
  • filamin-2
  • filamin-C
  • gamma-filamin
  • ABP-L, gamma filamin
  • filamin 2
  • 260kDa actin-binding protein
  • cgABP260 actin-binding domain
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