FMO3 Produkte
(Flavin Containing Monooxygenase 3 (FMO3))
Kategorien
Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor. In healthy individuals, trimethylamine is primarily converted to the non odorous trimethylamine N-oxide.[provided by RefSeq, Aug 2009].
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Ausgewählte FMO3 Kategorien
FMO3 Antikörper
High quality antibodies with extensive validation data.
FMO3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FMO3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (5)
Kat. Nr.
ABIN7267216
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), FACS
Validierungen
- (3)
Kat. Nr.
ABIN390888
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN515768
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene FMO3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354250
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7423360
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2721250
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FMO3 Produkten
: "Expression and genomic status of EGFR and ErbB-2 in alveolar and embryonal rhabdomyosarcoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 19, Issue 9, pp. 1213-20, (2006) (PubMed).: "Interindividual differences of human flavin-containing monooxygenase 3: genetic polymorphisms and functional variation." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 30, Issue 10, pp. 1043-52, (2002) (PubMed).
Synonyme und alternative Namen zu FMO3
flavin containing monooxygenase 3 (FMO3), flavin containing monooxygenase 3 (fmo3), flavin containing monooxygenase 3 L homeolog (fmo3.L), flavin containing monooxygenase 3 (Fmo3), AW111792, dJ127D3.1, FM03, FMOII, MGC107820, TMAUBezeichner auf Proteinebene für FMO3
- dimethylaniline monooxygenase [N-oxide-forming] 3
- flavin containing monooxygenase 3
- FMO 3
- FMO II
- FMO form 2
- dimethylaniline oxidase 3
- hepatic flavin-containing monooxygenase 3
- hepatic flavin-containing monooxygenase-3
- trimethylamine monooxygenase
- flavin-containing monooxygenase 3
- FMO 1D1
- flavin-containing monooxygenase FMO3
- flavin-containing monooxygenase form 3
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