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FMR1 Produkte

(Fragile X Mental Retardation 1 (FMR1))
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010].

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Ausgewählte FMR1 Kategorien

FMR1 Antikörper

High quality antibodies with extensive validation data.

FMR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

FMR1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FMR1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF, IHC (p), FACS
Validierungen
  • (16)
Kat. Nr. ABIN1498287
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Dog, Human, Monkey, Mouse, Rat
Applikation WB, IHC, IF, IHC (p), FACS
Validierungen
  • (16)
Kat. Nr. ABIN1491454
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Dog, Human, Monkey, Mouse, Rat
Applikation WB, IHC, IHC (p)
Validierungen
  • (11)
Kat. Nr. ABIN1491292
Menge 100 μL
Datenblatt Datenblatt

Empfohlene FMR1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955988
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6974787
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5654421
Menge 96 tests
Datenblatt Datenblatt

Empfohlene FMR1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1354256
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1354258
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7409242
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FMR1 Produkten

Yang, Arsenault, Bah, Krzeminski, Fekete, Chao, Pacey, Wang, Forman-Kay, Hampson, Wang: "Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain." in: Molecular psychiatry, (2018) (PubMed).

Zhou, Ye, Yang, Zhou, Zhao, Sun, Gao, Yi, Long: "A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14." in: Neuroscience, Vol. 349, pp. 64-75, (2018) (PubMed).

Majumder, House, Palanisamy, Qie, Day, Neskey, Diehl, Palanisamy: "RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC." in: PLoS genetics, Vol. 12, Issue 9, pp. e1006306, (2017) (PubMed).

Bartley, OKeefe, Blice-Baum, Mihailescu, Gong, Miyares, Karaca, Bordey: "Mammalian FMRP S499 Is Phosphorylated by CK2 and Promotes Secondary Phosphorylation of FMRP." in: eNeuro, Vol. 3, Issue 6, (2017) (PubMed).

Reynolds, Smith, Jefferson, Lugo: "Comparison of Equivalence between Two Commercially Available S499-Phosphorylated FMRP Antibodies in Mice." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143134, (2016) (PubMed).

Guimarães-Souza, Perche, Morgans, Duvoisin, Calaza: "Fragile X Mental Retardation Protein expression in the retina is regulated by light." in: Experimental eye research, Vol. 146, pp. 72-82, (2016) (PubMed).

Bartley, OKeefe, Bordey: "FMRP S499 is phosphorylated independent of mTORC1-S6K1 activity." in: PLoS ONE, Vol. 9, Issue 5, pp. e96956, (2015) (PubMed).

Subramanian, Dubini, Astling, Laurens, Old, Grossman, Posewitz, Seibert: "Profiling Chlamydomonas metabolism under dark, anoxic H2-producing conditions using a combined proteomic, transcriptomic, and metabolomic approach." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5431-51, (2014) (PubMed).

Zhou, Cao, Guo, Zhao, Wang, Jia, Li, Wang, Gabriel, Xue, Yi, Cui, Jin, Wang, Deng: "Fragile X mental retardation protein stimulates ribonucleoprotein assembly of influenza A virus." in: Nature communications, Vol. 5, pp. 3259, (2014) (PubMed).

Schutzius, Bleckmann, Kapps-Fouthier, di Giorgio, Gerhartz, Weiss: "A quantitative homogeneous assay for fragile X mental retardation 1 protein." in: Journal of neurodevelopmental disorders, Vol. 5, Issue 1, pp. 8, (2013) (PubMed).

Synonyme und alternative Namen zu FMR1

CG6203 gene product from transcript CG6203-RC (Fmr1), fragile X mental retardation 1 (FMR1), fragile X mental retardation 1 (Fmr1), fragile X mental retardation 1 (fmr1), fragile X mental retardation syndrome 1 (Fmr1), AT24755, BcDNA:GM08679, CG6203, cg6203, dFMR, dfmr, dFMR1, dFmr1, dfmr1, dFMRP, dFmrp, dFXR, dfxr, dFXR1, dfxr1, dFXRP, Dmel\\CG6203, dmfr1, EP(3)3517, FMR, fmr, Fmr-1, FMR1, fmr1, FMRP, FMRp, Fmrp, FRAXA, FXR, POF, POF1, zFMR1

Bezeichner auf Proteinebene für FMR1

  • CG6203-PA
  • CG6203-PB
  • CG6203-PC
  • CG6203-PD
  • CG6203-PE
  • CG6203-PF
  • CG6203-PG
  • CG6203-PH
  • CG6203-PI
  • Fmr1-PA
  • Fmr1-PB
  • Fmr1-PC
  • Fmr1-PD
  • Fmr1-PE
  • Fmr1-PF
  • Fmr1-PG
  • Fmr1-PH
  • Fmr1-PI
  • Fragile-X mental retardation protein
  • Fragile-X-related
  • dFmr1
  • drosophila fragile X mental retardation protein
  • fragile X
  • fragile X mental retardation
  • fragile X mental retardation 1
  • fragile X mental retardation gene
  • fragile X mental retardation protein
  • fragile X protein
  • fragile X related protein
  • fragile X-related
  • fragile x related
  • fragile-X
  • fragile X mental retardation protein 1
  • fragile X mental retardation protein 1 homolog
  • fragile X mental retardation syndrome 1 homolog
  • fragile X mental retardation-1 protein
  • protein FMR-1
  • ragile X mental retardation protein
  • fragile X mental retardation 1 protein
  • FMRP
  • mFmr1p
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