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FOXN1 Produkte

(Forkhead Box N1 (FOXN1))

Kategorien

The protein encoded by this gene is part of the forkhead family or 'winged-helix' transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. This gene family has over 100 members, subdivided into classes (A-Q) based on phylogeny. The encoded protein is proposed to regulate development of the thymus and differentiation of keratinocytes. Mutations in this gene cause severe primary T-cell immunodeficiency and congenital alopecia. In mouse mutations of this gene underlie the phenotype of the nude mouse, which has been widely used as a model system in oncology, immunology, dermatology, and transplantation studies. In humans mutations in this gene have been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013].

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Ausgewählte FOXN1 Kategorien

FOXN1 Antikörper

High quality antibodies with extensive validation data.

FOXN1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FOXN1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN1387592
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7153070
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, FACS
Validierungen
  • (2)
Kat. Nr. ABIN655992
Menge 400 μL
Datenblatt Datenblatt

Empfohlene FOXN1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1787167
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3135432
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3092648
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FOXN1 Produkten

Volpi, Yamazaki, Brauer, van Rooijen, Hayashida, Slavotinek, Sun Kuehn, Di Rocco, Rivolta, Bortolomai, Du, Felgentreff, Ott de Bruin, Hayashida, Freedman, Marcovecchio, Capuder, Rath, Luche, Hagedorn et al.: "EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay. ..." in: The Journal of experimental medicine, Vol. 214, Issue 3, pp. 623-637, (2017) (PubMed).

Schlake, Schorpp, Maul-Pavicic, Malashenko, Boehm: "Forkhead/winged-helix transcription factor Whn regulates hair keratin gene expression: molecular analysis of the nude skin phenotype." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 217, Issue 4, pp. 368-76, (2000) (PubMed).

Synonyme und alternative Namen zu FOXN1

forkhead box N1 (FOXN1), forkhead box N1 (foxn1), forkhead box N1 (foxN1), forkhead box protein N1 (LOC100125524), forkhead box N1 (Foxn1), D11Bhm185e, Fkh19, FKHL20, foxN, FOXN1, foxN1, foxn1, HFH-11, Hfh11, nu, nude, Rnu, RONU, WHN, Whn, whnb

Bezeichner auf Proteinebene für FOXN1

  • forkhead box protein N1
  • forkhead box N1
  • forkhead box N protein
  • forkhead box protein N1-like
  • transcription factor Forkhead box protein N1
  • Rowett nude
  • winged helix nude
  • winged-helix nude
  • winged-helix transcription factor nude
  • HNF-3/forkhead homolog 11
  • hepatocyte nuclear factor 3 forkhead homolog 11
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