FTO Produkte
(Fat Mass and Obesity-Associated (FTO))
Kategorien
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011].
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Ausgewählte FTO Kategorien
FTO Antikörper
High quality antibodies with extensive validation data.
FTO ELISA Kits
Reliable ELISA kits for a wide range of species.
FTO Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FTO Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7127502
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), FACS
Validierungen
- (3)
Kat. Nr.
ABIN390964
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IP
Validierungen
- (3)
Kat. Nr.
ABIN1169073
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene FTO ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966656
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5594574
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6228458
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FTO Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354483
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN1344345
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN1344349
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FTO Produkten
: "m6A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2." in: Nature communications, Vol. 10, Issue 1, pp. 5332, (2020) (PubMed).: "Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates." in: Nature chemical biology, Vol. 15, Issue 9, pp. 865-871, (2019) (PubMed).
: "N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response." in: Molecular cell, Vol. 69, Issue 4, pp. 636-647.e7, (2019) (PubMed).
: "N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications." in: Nature neuroscience, Vol. 21, Issue 2, pp. 195-206, (2019) (PubMed).
: "Dynamic m6A modification regulates local translation of mRNA in axons." in: Nucleic acids research, Vol. 46, Issue 3, pp. 1412-1423, (2019) (PubMed).
: "The Role of The RNA Demethylase FTO (Fat Mass and Obesity-Associated) and mRNA Methylation in Hippocampal Memory Formation." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 42, Issue 7, pp. 1502-1510, (2017) (PubMed).
: "FTO modulates circadian rhythms and inhibits the CLOCK-BMAL1-induced transcription." in: Biochemical and biophysical research communications, Vol. 464, Issue 3, pp. 826-32, (2015) (PubMed).
: "N6-adenosine methylation in MiRNAs." in: PLoS ONE, Vol. 10, Issue 2, pp. e0118438, (2015) (PubMed).
: "Dynamic m(6)A mRNA methylation directs translational control of heat shock response." in: Nature, Vol. 526, Issue 7574, pp. 591-4, (2015) (PubMed).
: "The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. ..." in: Science (New York, N.Y.), Vol. 318, Issue 5855, pp. 1469-72, (2007) (PubMed).
Synonyme und alternative Namen zu FTO
FTO, alpha-ketoglutarate dependent dioxygenase (FTO), fat mass and obesity associated (Fto), FTO, alpha-ketoglutarate dependent dioxygenase (Fto), fat mass and obesity associated L homeolog (fto.L), AW743446, mKIAA1752, RGD1305121Bezeichner auf Proteinebene für FTO
- alpha-ketoglutarate-dependent dioxygenase FTO
- fat mass and obesity-associated protein
- protein fto
- protein fatso
- fat mass and obesity associated protein
- Protein fatso
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