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FUS Produkte

(Fused in Sarcoma (FUS))
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009].

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Ausgewählte FUS Kategorien

FUS Antikörper

High quality antibodies with extensive validation data.

FUS ELISA Kits

Reliable ELISA kits for a wide range of species.

FUS Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FUS Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Cow, Dog, Human, Mouse, Pig, Rabbit, Rat
Applikation WB, IHC
Validierungen
  • (6)
Kat. Nr. ABIN2778717
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC, IF, FACS
Validierungen
  • (7)
Kat. Nr. ABIN3031006
Menge 0.4 mL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, IHC (p), FACS
Validierungen
  • (4)
Kat. Nr. ABIN654146
Menge 400 μL
Datenblatt Datenblatt

Empfohlene FUS ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966914
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1156242
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN858233
Menge 96 tests
Datenblatt Datenblatt

Empfohlene FUS Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123020
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (5)
  • (1)
Kat. Nr. ABIN2721461
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Human respiratory syncytial virus B
Source Yeast
Validierungen
  • (1)
Kat. Nr. ABIN5714278
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FUS Produkten

Martinez-Macias, Moore, Green, Gomez-Herreros, Naumann, Hermann, Van Damme, Hafezparast, Caldecott: "FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I-induced DNA breakage and transcriptional stress." in: Life science alliance, Vol. 2, Issue 2, (2019) (PubMed).

Singatulina, Hamon, Sukhanova, Desforges, Joshi, Bouhss, Lavrik, Pastré: "PARP-1 Activation Directs FUS to DNA Damage Sites to Form PARG-Reversible Compartments Enriched in Damaged DNA." in: Cell reports, Vol. 27, Issue 6, pp. 1809-1821.e5, (2019) (PubMed).

Mori, Honda, Ishii, Yoshimura, Sasagasako, Suzuki, Taniwaki, Iwaki: "Expanded polyglutamine impairs normal nuclear distribution of fused in sarcoma and poly (rC)-binding protein 1 in Huntington's disease." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 39, Issue 5, pp. 358-367, (2019) (PubMed).

Gittings, Foti, Benson, Gami-Patel, Isaacs, Lashley: "Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS." in: Acta neuropathologica communications, Vol. 7, Issue 1, pp. 18, (2019) (PubMed).

Li, Song, Moh, Kim, Kim: "Cytoplasmic Restriction of Mutated SOD1 Impairs the DNA Repair Process in Spinal Cord Neurons." in: Cells, Vol. 8, Issue 12, (2019) (PubMed).

Pansarasa, Bordoni, Drufuca, Diamanti, Sproviero, Trotti, Bernuzzi, La Salvia, Gagliardi, Ceroni, Cereda: "Lymphoblastoid cell lines as a model to understand amyotrophic lateral sclerosis disease mechanisms." in: Disease models & mechanisms, Vol. 11, Issue 3, (2018) (PubMed).

Moore, Blachere, Fak, Park, Sawicka, Parveen, Zucker-Scharff, Moltedo, Rudensky, Darnell: "ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity." in: eLife, Vol. 7, (2018) (PubMed).

Wang, Grunseich, Fox, Burdick, Zhu, Ravazian, Hafner, Cheung: "Human proteins that interact with RNA/DNA hybrids." in: Genome research, Vol. 28, Issue 9, pp. 1405-1414, (2018) (PubMed).

Bogaert, Boeynaems, Kato, Guo, Caulfield, Steyaert, Scheveneels, Wilmans, Haeck, Hersmus, Schymkowitz, Rousseau, Shorter, Callaerts, Robberecht, Van Damme, Van Den Bosch: "Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity." in: Cell reports, Vol. 24, Issue 3, pp. 529-537.e4, (2018) (PubMed).

Gorthi, Romero, Loranc, Cao, Lawrence, Goodale, Iniguez, Bernard, Masamsetti, Roston, Lawlor, Toretsky, Stegmaier, Lessnick, Chen, Bishop: "EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma." in: Nature, Vol. 555, Issue 7696, pp. 387-391, (2018) (PubMed).

Synonyme und alternative Namen zu FUS

FUS RNA binding protein (FUS), fused in sarcoma (Fus), FUS RNA binding protein (Fus), fused in sarcoma (FUS), ALS6, D430004D17Rik, D930039C12Rik, ETM4, FUS/TLS, FUS1, Fus1, HNRNPP2, POMP75, TLS, Tls

Bezeichner auf Proteinebene für FUS

  • 75 kDa DNA-pairing protein
  • RNA-binding protein FUS
  • fus-like protein
  • fusion gene in myxoid liposarcoma
  • heterogeneous nuclear ribonucleoprotein P2
  • oncogene FUS
  • oncogene TLS
  • translocated in liposarcoma protein
  • fusion, derived from t(12;16) malignant liposarcoma
  • hnRNP P2
  • pigpen protein
  • protein pigpen
  • translocated in liposarcoma
  • fusion
  • pigpen
  • fusion (involved in t(12;16) in malignant liposarcoma)
  • 16) in malignant liposarcoma)
  • 16) malignant liposarcoma
  • fusion (involved in t(12
  • fusion, derived from t(12
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