FXYD1 Produkte
(FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))
Kategorien
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature. [provided by RefSeq, Jul 2008].
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Ausgewählte FXYD1 Kategorien
FXYD1 Antikörper
High quality antibodies with extensive validation data.
FXYD1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FXYD1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7236228
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN3043831
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1882173
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene FXYD1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2728859
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FXYD1 Produkten
: "Phospholemman and beta-adrenergic stimulation in the heart." in: American journal of physiology. Heart and circulatory physiology, Vol. 298, Issue 3, pp. H807-15, (2010) (PubMed).: "FXYD1, a modulator of Na,K-ATPase activity, facilitates female sexual development by maintaining gonadotrophin-releasing hormone neuronal excitability." in: Journal of neuroendocrinology, Vol. 21, Issue 2, pp. 108-22, (2009) (PubMed).
: "Extracellular potassium dependence of the Na+-K+-ATPase in cardiac myocytes: isoform specificity and effect of phospholemman." in: American journal of physiology. Cell physiology, Vol. 297, Issue 3, pp. C699-705, (2009) (PubMed).
: "Left ventricular function of isoproterenol-induced hypertrophied rat hearts perfused with blood: mechanical work and energetics." in: American journal of physiology. Heart and circulatory physiology, Vol. 297, Issue 5, pp. H1736-43, (2009) (PubMed).
Synonyme und alternative Namen zu FXYD1
FXYD domain containing ion transport regulator 1 (FXYD1), FXYD domain-containing ion transport regulator 1 (Fxyd1), 0610012C17Rik, 1110006M24Rik, PLM, Plm, PmlBezeichner auf Proteinebene für FXYD1
- FXYD domain containing ion transport regulator 1
- phospholemman
- FXYD domain containing ion transport regulator 1 (phospholemman)
- FXYD domain-containing ion transport regulator 1
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