GABRA1 Produkte
(gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
Kategorien
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte GABRA1 Kategorien
GABRA1 Antikörper
High quality antibodies with extensive validation data.
GABRA1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GABRA1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Applikation
WB, ICC, IF, AA
Validierungen
- (4)
Kat. Nr.
ABIN863138
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, ICC, IF
Validierungen
- (4)
Kat. Nr.
ABIN2485717
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, ICC, IF
Validierungen
- (4)
Kat. Nr.
ABIN2485726
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene GABRA1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6228560
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene GABRA1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1354645
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123050
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GABRA1 Produkten
: "Corticotropin-Releasing Factor Receptor-1 Neurons in the Lateral Amygdala Display Selective Sensitivity to Acute and Chronic Ethanol Exposure." in: eNeuro, Vol. 7, Issue 2, (2020) (PubMed).: "Strain-specific programming of prenatal ethanol exposure across generations." in: Alcohol (Fayetteville, N.Y.), Vol. 60, pp. 191-199, (2017) (PubMed).
: "α2 Subunit-Containing GABAA Receptor Subtypes Are Upregulated and Contribute to Alcohol-Induced Functional Plasticity in the Rat Hippocampus." in: Molecular pharmacology, Vol. 92, Issue 2, pp. 101-112, (2017) (PubMed).
: "How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs." in: Neuron, Vol. 91, Issue 4, pp. 792-807, (2016) (PubMed).
: "Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9526-39, (2016) (PubMed).
: "Role of microRNA-4458 in patients with non-small-cell lung cancer." in: Oncology letters, Vol. 12, Issue 5, pp. 3958-3966, (2016) (PubMed).
: "The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration." in: Nature neuroscience, Vol. 18, Issue 7, pp. 988-96, (2015) (PubMed).
: "The developmental evolution of the seizure phenotype and cortical inhibition in mouse models of juvenile myoclonic epilepsy." in: Neurobiology of disease, Vol. 82, pp. 164-175, (2015) (PubMed).
: "GABAergic interneuronal loss and reduced inhibitory synaptic transmission in the hippocampal CA1 region after mild traumatic brain injury." in: Experimental neurology, Vol. 273, pp. 11-23, (2015) (PubMed).
: "Seizure-related regulation of GABAA receptors in spontaneously epileptic rats." in: Neurobiology of disease, Vol. 77, pp. 246-56, (2015) (PubMed).
Synonyme und alternative Namen zu GABRA1
gamma-aminobutyric acid type A receptor alpha1 subunit (GABRA1), gamma-aminobutyric acid type A receptor alpha1 subunit (Gabra1), gamma-aminobutyric acid (GABA) A receptor, alpha 1 (gabra1), gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 (Gabra1), gamma-aminobutyric acid receptor subunit alpha-1 (LOC100653509), ECA4, EJM, EJM5, Gabra-1, zgc:153566Bezeichner auf Proteinebene für GABRA1
- GABA(A) receptor subunit alpha-1
- GABA(A) receptor, alpha 1
- gamma-aminobutyric acid receptor subunit alpha-1
- gamma-aminobutyric acid A receptor, alpha 1
- gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1
- gamma-aminobutyric acid A receptor, alpha 1
- gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
- GABAA alpha 1
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