GABRA4 Produkte
(gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4))
Kategorien
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011].
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Ausgewählte GABRA4 Kategorien
GABRA4 Antikörper
High quality antibodies with extensive validation data.
GABRA4 ELISA Kits
Reliable ELISA kits for a wide range of species.
GABRA4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GABRA4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7153483
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC
Validierungen
- (3)
Kat. Nr.
ABIN3181674
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN2565552
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene GABRA4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6228561
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene GABRA4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN2565117
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354651
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7423147
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GABRA4 Produkten
: "Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus." in: Journal of neurochemistry, Vol. 133, Issue 4, pp. 489-500, (2015) (PubMed).: "Downregulation of Gabra4 expression during alcohol withdrawal is mediated by specific microRNAs in cultured mouse cortical neurons." in: Brain and behavior, Vol. 5, Issue 8, pp. e00355, (2015) (PubMed).
: "Altered intrathalamic GABAA neurotransmission in a mouse model of a human genetic absence epilepsy syndrome." in: Neurobiology of disease, Vol. 73C, pp. 407-417, (2014) (PubMed).
: "Chronic ethanol and withdrawal differentially modulate lateral/basolateral amygdala paracapsular and local GABAergic synapses." in: The Journal of pharmacology and experimental therapeutics, Vol. 337, Issue 1, pp. 162-70, (2011) (PubMed).
: "Distinct mechanisms regulate GABAA receptor and gephyrin clustering at perisomatic and axo-axonic synapses on CA1 pyramidal cells." in: The Journal of physiology, Vol. 589, Issue Pt 20, pp. 4959-80, (2011) (PubMed).
: "Mice lacking Gad2 show altered behavioral effects of ethanol, flurazepam and gabaxadol." in: Addiction biology, Vol. 15, Issue 1, pp. 45-61, (2009) (PubMed).
: "Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones." in: The Journal of physiology, Vol. 586, Issue 4, pp. 965-87, (2008) (PubMed).
: "Alcohol regulates gene expression in neurons via activation of heat shock factor 1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 47, pp. 12957-66, (2007) (PubMed).
: "Effect of chronic administration of ethanol on the regulation of tyrosine kinase phosphorylation of the GABAA receptor subunits in the rat brain." in: Neurochemical research, Vol. 32, Issue 7, pp. 1179-87, (2007) (PubMed).
: "Egr3 stimulation of GABRA4 promoter activity as a mechanism for seizure-induced up-regulation of GABA(A) receptor alpha4 subunit expression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 33, pp. 11894-9, (2005) (PubMed).
Synonyme und alternative Namen zu GABRA4
gamma-aminobutyric acid type A receptor alpha4 subunit (GABRA4), gamma-aminobutyric acid type A receptor alpha4 subunit (Gabra4), gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4 (Gabra4), Gabra-4, GABRA4Bezeichner auf Proteinebene für GABRA4
- gamma-aminobutyric acid (GABA) A receptor, alpha 4
- gamma-aminobutyric acid A receptor, alpha 4
- GABA(A) receptor subunit alpha-4
- gamma-aminobutyric acid receptor subunit alpha-4-like
- GABA-A receptor alpha-4 subunit
- gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 4
- gamma-aminobutyric acid receptor subunit alpha-4
- GABA(A) receptor, alpha 4
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