GAD65 Produkte
(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
Kategorien
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008].
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Ausgewählte GAD65 Kategorien
GAD65 Antikörper
High quality antibodies with extensive validation data.
GAD65 ELISA Kits
Reliable ELISA kits for a wide range of species.
GAD65 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GAD65 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7433339
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (6)
Kat. Nr.
ABIN949999
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7437707
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene GAD65 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967053
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967052
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956137
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene GAD65 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN1354671
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Baculovirus infected Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN7320200
Menge
20 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Baculovirus infected Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN7320201
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GAD65 Produkten
: "Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy." in: The Journal of cell biology, Vol. 215, Issue 2, pp. 245-258, (2016) (PubMed).: "Early GABAergic transmission defects in the external globus pallidus and rest/activity rhythm alteration in a mouse model of Huntington's disease." in: Neuroscience, Vol. 329, pp. 363-79, (2016) (PubMed).
: "Feedback modulation of neural network synchrony and seizure susceptibility by Mdm2-p53-Nedd4-2 signaling." in: Molecular brain, Vol. 9, pp. 32, (2016) (PubMed).
: "Antibodies to inhibitory synaptic proteins in neurological syndromes associated with glutamic acid decarboxylase autoimmunity." in: PLoS ONE, Vol. 10, Issue 3, pp. e0121364, (2015) (PubMed).
: "Neuron-astrocyte interaction enhance GABAergic synaptic transmission in a manner dependent on key metabolic enzymes." in: Frontiers in cellular neuroscience, Vol. 9, pp. 120, (2015) (PubMed).
: "Vesicular glutamate transporter 1 orchestrates recruitment of other synaptic vesicle cargo proteins during synaptic vesicle recycling." in: The Journal of biological chemistry, Vol. 290, Issue 37, pp. 22593-601, (2015) (PubMed).
: "Acrylamide neurotoxicity on the cerebrum of weaning rats." in: Neural regeneration research, Vol. 10, Issue 6, pp. 938-43, (2015) (PubMed).
: "The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 37, pp. 12289-303, (2014) (PubMed).
: "Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons." in: Neuroscience, Vol. 246, pp. 451-67, (2013) (PubMed).
: "Prenatal stress affects network properties of rat hippocampal neurons." in: Biological psychiatry, Vol. 73, Issue 11, pp. 1095-102, (2013) (PubMed).
Synonyme und alternative Namen zu GAD65
glutamate decarboxylase 2 (GAD2), glutamate decarboxylase 2 (PTRG_06148), glutamate decarboxylase 2 (LOC9324534), glutamate decarboxylase 2 (Gad2), glutamate decarboxylase 1 (GAD1), glutamate decarboxylase 2 (gad2), glutamic acid decarboxylase 2 (Gad2), 6330404F12Rik, F12P19.12, F12P19_12, GAD(65), Gad-2, GAD65, gad65, GLUTAMATE DECARBOXYLASE 2, glutamate decarboxylase 2, zgc:112198Bezeichner auf Proteinebene für GAD65
- glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
- glutamate decarboxylase 2
- glutamic acid decarboxylase
- 65 kDa glutamic acid decarboxylase
- GAD-65
- Glutamate decarboxylase 2 (islet)
- glutamate decarboxylase 65 kDa isoform
- glutamic acid decarboxylase 2
- glutamic acid decarboxylase 65
- Glutamate decarboxylase-2 (pancreas)
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