GADD45A Produkte
(Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
Kategorien
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010].
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Ausgewählte GADD45A Kategorien
GADD45A Antikörper
High quality antibodies with extensive validation data.
GADD45A ELISA Kits
Reliable ELISA kits for a wide range of species.
GADD45A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GADD45A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (6)
Kat. Nr.
ABIN6140923
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN685432
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN650724
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene GADD45A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6975062
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956310
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956311
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene GADD45A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354677
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354675
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505208
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GADD45A Produkten
: "The Natural Compound Neobractatin Induces Cell Cycle Arrest by Regulating E2F1 and Gadd45α." in: Frontiers in oncology, Vol. 9, pp. 654, (2019) (PubMed).: "Significance of S100P as a biomarker in diagnosis, prognosis and therapy of opisthorchiasis-associated cholangiocarcinoma." in: International journal of cancer. Journal international du cancer, (2015) (PubMed).
: "CArG-driven GADD45α activated by resveratrol inhibits lung cancer cells." in: Genes & cancer, Vol. 6, Issue 5-6, pp. 220-30, (2015) (PubMed).
: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." in: International journal of nanomedicine, Vol. 9, pp. 4829-46, (2014) (PubMed).
: "p53 controls hepatitis C virus non-structural protein 5A-mediated downregulation of GADD45α expression via the NF-κB and PI3K-Akt pathways." in: The Journal of general virology, Vol. 94, Issue Pt 2, pp. 326-35, (2013) (PubMed).
: "Inhibition of NF-?B activation sensitizes U937 cells to 3'-azido-3'-deoxythymidine induced apoptosis." in: Cell death & disease, Vol. 1, pp. e81, (2011) (PubMed).
: "Methylation-mediated repression of GADD45alpha in prostate cancer and its role as a potential therapeutic target." in: Cancer research, Vol. 69, Issue 4, pp. 1527-35, (2009) (PubMed).
: "Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells." in: Neoplasia (New York, N.Y.), Vol. 10, Issue 5, pp. 471-80, (2008) (PubMed).
Synonyme und alternative Namen zu GADD45A
growth arrest and DNA damage inducible alpha L homeolog (gadd45a.L), growth arrest and DNA-damage-inducible, alpha, b (gadd45ab), growth arrest and DNA damage inducible alpha (GADD45A), growth arrest and DNA damage inducible alpha (gadd45a), growth arrest and DNA damage-inducible protein 45 (GADD45), growth arrest and DNA-damage-inducible 45 alpha (Gadd45a), growth arrest and DNA-damage-inducible, alpha (Gadd45a), AA545191, ddit1, Ddit1, DDIT1, gadd45, GADD45, Gadd45, gadd45a, GADD45A, MGC53491, zgc:91795Bezeichner auf Proteinebene für GADD45A
- growth arrest and DNA-damage-inducible, alpha
- growth arrest and DNA damage-inducible protein GADD45 alpha
- growth arrest and DNA-damage-inducible protein 45 alpha
- growth arrest and DNA-damage-inducible protein alpha
- growth arrest and DNA damage-inducible protein 45
- Growth arrest and DNA-damage-inducible protein GADD45 alpha
- DDIT-1
- DNA damage-inducible transcript 1 protein
- DNA-damage inducible transcript 1
- DNA-damage-inducible transcript 1
- Gadd45alpha
- growth arrest and DNA-damage-inducible protein GADD45 alpha
- DNA damage-inducible transcript-1
- growth arrest and DNA-damage-inducible 45 alpha
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