GCLC Produkte
(Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
Kategorien
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010].
antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.
Ausgewählte GCLC Kategorien
GCLC Antikörper
High quality antibodies with extensive validation data.
GCLC ELISA Kits
Reliable ELISA kits for a wide range of species.
GCLC Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GCLC Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (6)
- (7)
Kat. Nr.
ABIN561050
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, FACS, IHC (p)
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN655884
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Applikation
WB, IHC
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN2774078
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene GCLC ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6956167
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967068
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956168
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene GCLC Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123113
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354922
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354924
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GCLC Produkten
: "Overexpression of Brg1 Alleviates Hepatic Ischemia/Reperfusion-Induced Acute Lung Injury through Antioxidative Stress Effects." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 8787392, (2018) (PubMed).: "Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks." in: Biological trace element research, Vol. 186, Issue 1, pp. 226-237, (2018) (PubMed).
: "Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice." in: PLoS ONE, Vol. 13, Issue 5, pp. e0198139, (2018) (PubMed).
: "Oregano Essential Oil Induces SOD1 and GSH Expression through Nrf2 Activation and Alleviates Hydrogen Peroxide-Induced Oxidative Damage in IPEC-J2 Cells." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 5987183, (2017) (PubMed).
: "Silymarin protects against acrylamide-induced neurotoxicity via Nrf2 signalling in PC12 cells." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 102, pp. 93-101, (2017) (PubMed).
: "Bone marrow mesenchymal stem cells protect against bleomycin-induced pulmonary fibrosis in rat by activating Nrf2 signaling." in: International journal of clinical and experimental pathology, Vol. 8, Issue 7, pp. 7752-61, (2016) (PubMed).
: "Electroacupuncture alleviates cerebral ischemia and reperfusion injury via modulation of the ERK1/2 signaling pathway." in: Neural regeneration research, Vol. 11, Issue 7, pp. 1090-8, (2016) (PubMed).
: "Inhibition of Glutathione Production Induces Macrophage CD36 Expression and Enhances Cellular-oxidized Low Density Lipoprotein (oxLDL) Uptake." in: The Journal of biological chemistry, Vol. 290, Issue 36, pp. 21788-99, (2015) (PubMed).
: "Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus." in: PLoS ONE, Vol. 9, Issue 4, pp. e94460, (2014) (PubMed).
: "Glycogen synthase kinase 3 regulates cell death and survival signaling in tumor cells under redox stress." in: Neoplasia (New York, N.Y.), Vol. 16, Issue 9, pp. 710-22, (2014) (PubMed).
Synonyme und alternative Namen zu GCLC
glutamate-cysteine ligase catalytic subunit (GCLC), glutamate-cysteine ligase, catalytic subunit (gclc), Glutamate-cysteine ligase catalytic subunit (Gclc), gamma glutamylcysteine synthetase (LbGCS), gamma glutamylcysteine synthetase (gcsA), glutamate-cysteine ligase, catalytic subunit L homeolog (gclc.L), glutamate-cysteine ligase, catalytic subunit S homeolog (gclc.S), gamma-glutamylcysteine synthetase (GSH1), glutamate-cysteine ligase, catalytic subunit (Gclc), glutamate-cysteine ligase catalytic subunit (Gclc), 2259, cb1049, CG2259, D9Wsu168e, DDBDRAFT_0186120, DDBDRAFT_0231403, DDB_0186120, DDB_0231403, Dmel\\CG2259, DmGCLC, DmGCS, DmGCSh, fe36e11, GCL, GCLC, gclc, GCLc, Gcs, GCS, GCSh, Gcsh, Ggcs-hs, GLCL, GLCL-H, GLCLC, Glclc, MGC146287, wu:fe36e11Bezeichner auf Proteinebene für GCLC
- glutamate--cysteine ligase catalytic subunit
- glutamate-cysteine ligase, catalytic subunit
- CG2259-PA
- CG2259-PB
- Gclc-PA
- Gclc-PB
- gamma-Glutamylcysteine synthetase
- gamma-Glutamylcysteine synthetase catalytic subunit
- gamma-glutamylcysteine ligase
- glutamate cysteine ligase
- glutamate-cysteine ligase
- gamma glutamylcysteine synthetase
- gamma-ECS
- glutamate--cysteine ligase, chloroplastic
- GCS heavy chain
- gamma-glutamylcysteine synthetase
- gamma GCS-HS
- gamma-glutamylcysteine synthetase heavy subunit
- Glutamylcysteine gamma synthetase light chain
- glutamate-cysteine ligase catalytic subunit
Sie sind hier:
