GCLM Produkte
(Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
Kategorien
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq, Jul 2008].
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Ausgewählte GCLM Kategorien
GCLM Antikörper
High quality antibodies with extensive validation data.
GCLM ELISA Kits
Reliable ELISA kits for a wide range of species.
GCLM Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GCLM Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IF, FACS, IHC (p)
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN653046
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (11)
Kat. Nr.
ABIN7433051
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA, IF
Validierungen
- (4)
Kat. Nr.
ABIN7154002
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene GCLM ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967070
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967069
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956169
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene GCLM Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1354926
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7411648
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7411642
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GCLM Produkten
: "A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity." in: Cell reports, Vol. 26, Issue 6, pp. 1544-1556.e8, (2019) (PubMed).: "Oregano Essential Oil Induces SOD1 and GSH Expression through Nrf2 Activation and Alleviates Hydrogen Peroxide-Induced Oxidative Damage in IPEC-J2 Cells." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 5987183, (2017) (PubMed).
: "Silymarin protects against acrylamide-induced neurotoxicity via Nrf2 signalling in PC12 cells." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 102, pp. 93-101, (2017) (PubMed).
: "Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 33, pp. E4600-9, (2015) (PubMed).
: "Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice." in: Free radical biology & medicine, Vol. 68, pp. 148-58, (2014) (PubMed).
: "The protective role of resveratrol in the sodium arsenite-induced oxidative damage via modulation of intracellular GSH homeostasis." in: Biological trace element research, Vol. 155, Issue 1, pp. 119-31, (2014) (PubMed).
: "Mechanism and significance of changes in glutamate-cysteine ligase expression during hepatic fibrogenesis." in: The Journal of biological chemistry, Vol. 287, Issue 43, pp. 36341-55, (2012) (PubMed).
: "Molecular and functional characterizations of gastrula organizer cells derived from human embryonic stem cells." in: Stem cells (Dayton, Ohio), Vol. 29, Issue 4, pp. 600-8, (2011) (PubMed).
: "Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway." in: Toxicology and applied pharmacology, Vol. 255, Issue 2, pp. 176-83, (2011) (PubMed).
: "Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 38, Issue 12, pp. 2293-301, (2010) (PubMed).
Synonyme und alternative Namen zu GCLM
glutamate-cysteine ligase regulatory subunit (PTRG_09814), glutamate cysteine ligase, modifier subunit (Gclm), glutamate-cysteine ligase modifier subunit (GCLM), glutamate-cysteine ligase, modifier subunit (gclm), glutamate-cysteine ligase, modifier subunit L homeolog (gclm.L), glutamate-cysteine ligase, modifier subunit (Gclm), glutamate-cysteine ligase modifier subunit (Gclm), AI649393, Gcmc, Glclr, GLCLR, id:ibd3182, wu:fi24c07, zgc:55903Bezeichner auf Proteinebene für GCLM
- glutamate-cysteine ligase regulatory subunit
- GCS light chain
- gamma-ECS regulatory subunit
- gamma-glutamylcysteine synthetase regulatory subunit
- glutamate cysteine ligase (gamma-glutamylcysteine synthetase), regulatory
- glutamate--cysteine ligase regulatory subunit
- glutamate-cysteine ligase modifier subunit
- GSC light chain
- glutamate--cysteine ligase modifier subunit
- glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD)
- glutamate-cysteine ligase modifier subunit delta2 alternative splicing
- glutamate-cysteine ligase regulatory protein
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