GFI1 Produkte
(Growth Factor Independent 1 (GFI1))
Kategorien
This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte GFI1 Kategorien
GFI1 Antikörper
High quality antibodies with extensive validation data.
GFI1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GFI1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), IF
Validierungen
- (5)
Kat. Nr.
ABIN561035
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7245050
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN969174
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene GFI1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6222660
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene GFI1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1355013
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3092738
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3134645
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GFI1 Produkten
: "Transcription factor induced conversion of human fibroblasts towards the hair cell lineage." in: PLoS ONE, Vol. 13, Issue 7, pp. e0200210, (2019) (PubMed).: "GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1." in: Nature communications, Vol. 9, Issue 1, pp. 1418, (2018) (PubMed).
: "Single-cell analysis of mixed-lineage states leading to a binary cell fate choice." in: Nature, Vol. 537, Issue 7622, pp. 698-702, (2017) (PubMed).
: "Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1." in: PLoS ONE, Vol. 11, Issue 7, pp. e0160344, (2017) (PubMed).
: "Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma. ..." in: Nature, Vol. 511, Issue 7510, pp. 428-34, (2014) (PubMed).
: "Role of oncoprotein growth factor independent-1 (GFI1) in repression of 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1): a comparative analysis in human prostate cancer and kidney cells." in: The Journal of steroid biochemistry and molecular biology, Vol. 103, Issue 3-5, pp. 742-6, (2007) (PubMed).
: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, (2006) (PubMed).
Synonyme und alternative Namen zu GFI1
growth factor independent 1 (Gfi1), growth factor independent 1 transcriptional repressor (GFI1), growth factor independent 1 transcriptional repressor (Gfi1), AW495828, Gfi-1, GFI-1, GFI1, GFI1A, Pal-1, Pal1, SCN2, ZNF163Bezeichner auf Proteinebene für GFI1
- growth factor independent protein 1
- zinc finger protein Gfi-1
- growth factor independent 1
- Growth factor independent-1
- growth factor independence-1
- zinc finger protein 163
- growth factor independence 1
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