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GLRA1 Produkte

(Glycine Receptor, alpha 1 (GLRA1))

Kategorien

The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009].

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Ausgewählte GLRA1 Kategorien

GLRA1 Antikörper

High quality antibodies with extensive validation data.

GLRA1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene GLRA1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7154186
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (3)
Kat. Nr. ABIN3017068
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, ICC, FACS, Neut
Validierungen
  • (3)
Kat. Nr. ABIN5611339
Menge 100 μL
Datenblatt Datenblatt

Empfohlene GLRA1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6228771
Menge 96 tests
Datenblatt Datenblatt

Empfohlene GLRA1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1355226
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1355228
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren GLRA1 Produkten

Zou, Xia, Han, Liu, Xiong: "The synthetic cannabinoid dehydroxylcannabidiol restores the function of a major GABAA receptor isoform in a cell model of hyperekplexia." in: The Journal of biological chemistry, Vol. 295, Issue 1, pp. 138-145, (2020) (PubMed).

Lu, Fan, Zou, Hou, Pan, Guo, Yao, Du, Homanics, Liu, Zhang, Xiong: "Involvement of glycine receptor α1 subunits in cannabinoid-induced analgesia." in: Neuropharmacology, Vol. 133, pp. 224-232, (2018) (PubMed).

Ariño, Höftberger, Gresa-Arribas, Martínez-Hernández, Armangue, Kruer, Arpa, Domingo, Rojc, Bataller, Saiz, Dalmau, Graus: "Paraneoplastic Neurological Syndromes and Glutamic Acid Decarboxylase Antibodies." in: JAMA neurology, Vol. 72, Issue 8, pp. 874-81, (2015) (PubMed).

Wang, Lynch: "Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptor." in: The Journal of biological chemistry, Vol. 286, Issue 44, pp. 38814-24, (2011) (PubMed).

Schofield, Jenkins, Harrison: "A highly conserved aspartic acid residue in the signature disulfide loop of the alpha 1 subunit is a determinant of gating in the glycine receptor." in: The Journal of biological chemistry, Vol. 278, Issue 36, pp. 34079-83, (2003) (PubMed).

Chatterton, Awobuluyi, Premkumar, Takahashi, Talantova, Shin, Cui, Tu, Sevarino, Nakanishi, Tong, Lipton, Zhang: "Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits." in: Nature, Vol. 415, Issue 6873, pp. 793-8, (2002) (PubMed).

Craig, Lichtman: "Getting a bead on receptor movements." in: Nature neuroscience, Vol. 4, Issue 3, pp. 219-20, (2001) (PubMed).

Synonyme und alternative Namen zu GLRA1

glycine receptor alpha 1 (GLRA1), glycine receptor, alpha 1 (Glra1), glycine receptor, alpha 1 (glra1), glycine receptor, alpha 1 subunit (Glra1), B230397M16Rik, GLYRA1, HKPX1, nmf11, oscillator, ot, spasmodic, spd, STHE, [a]Z1

Bezeichner auf Proteinebene für GLRA1

  • glycine receptor, alpha 1 (startle disease/hyperekplexia)
  • glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)
  • glycine receptor, alpha 1
  • glycine receptor subunit alpha-1-like
  • glycine receptor 48 kDa subunit
  • glycine receptor strychnine-binding subunit
  • glycine receptor subunit alpha-1
  • glycine receptor, alpha 1 subunit
  • GlyR [a]Z1
  • glycine receptor subunit alphaZ1
  • glycine receptor, alphaZ1 subunit
  • glycine receptor alpha 1 subunit
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