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Glutamate Dehydrogenase 1 Produkte

(Glutamate Dehydrogenase 1 (GLUD1))
This gene encodes glutamate dehydrogenase protein\; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans.[provided by RefSeq, Sep 2009].

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Ausgewählte Glutamate Dehydrogenase 1 Kategorien

Glutamate Dehydrogenase 1 Antikörper

High quality antibodies with extensive validation data.

Glutamate Dehydrogenase 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Glutamate Dehydrogenase 1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Glutamate Dehydrogenase 1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC, IF
Validierungen
  • (8)
Kat. Nr. ABIN7263621
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, IF
Validierungen
  • (7)
Kat. Nr. ABIN6141157
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (6)
Kat. Nr. ABIN7267411
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Glutamate Dehydrogenase 1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962766
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956140
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956141
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Glutamate Dehydrogenase 1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Cow
Source Cow
Validierungen
Kat. Nr. ABIN2129438
Menge 1 kU
Datenblatt Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7389884
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN2129436
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Glutamate Dehydrogenase 1 Produkten

Geiszler, Ugun-Klusek, Lawler, Pardon, Yuchun, Bai, Daykin, Auer, Bedford: "Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons." in: Scientific reports, Vol. 8, Issue 1, pp. 4833, (2019) (PubMed).

Karri, Singh, Paripati, Marada, Krishnamoorthy, Guruprasad, Balasubramanian, Sepuri: "Adaptation of Mge1 to oxidative stress by local unfolding and altered Interaction with mitochondrial Hsp70 and Mxr2." in: Mitochondrion, (2018) (PubMed).

Rueda, Johnson, Giddabasappa, Swaroop, Brooks, Sigel, Chaney, Fox: "The cellular and compartmental profile of mouse retinal glycolysis, tricarboxylic acid cycle, oxidative phosphorylation, and ~P transferring kinases." in: Molecular vision, Vol. 22, pp. 847-85, (2016) (PubMed).

Knudsen, Balaji, Freinkman, McCue, Witkiewicz: "Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential." in: Oncotarget, Vol. 7, Issue 48, pp. 78396-78411, (2016) (PubMed).

Li, Li, Li, Zhong, Ji, Yu, Zhang, Wen, Zhang, Goscinski, Nesland, Suo: "PDHA1 gene knockout in prostate cancer cells results in metabolic reprogramming towards greater glutamine dependence." in: Oncotarget, Vol. 7, Issue 33, pp. 53837-53852, (2016) (PubMed).

Spanaki, Kotzamani, Plaitakis: "Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions." in: Neurochemical research, Vol. 42, Issue 1, pp. 92-107, (2016) (PubMed).

Spanaki, Kotzamani, Petraki, Drakos, Plaitakis: "Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues." in: Molecular and cellular endocrinology, Vol. 415, pp. 1-11, (2015) (PubMed).

Pougovkina, te Brinke, Ofman, van Cruchten, Kulik, Wanders, Houten, de Boer: "Mitochondrial protein acetylation is driven by acetyl-CoA from fatty acid oxidation." in: Human molecular genetics, Vol. 23, Issue 13, pp. 3513-22, (2015) (PubMed).

Jeong, Lee, Lee, Haigis: "SIRT4 protein suppresses tumor formation in genetic models of Myc-induced B cell lymphoma." in: The Journal of biological chemistry, Vol. 289, Issue 7, pp. 4135-44, (2014) (PubMed).

Yang, Ko, Hensley, Jiang, Wasti, Kim, Sudderth, Calvaruso, Lumata, Mitsche, Rutter, Merritt, DeBerardinis: "Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport." in: Molecular cell, Vol. 56, Issue 3, pp. 414-24, (2014) (PubMed).

Synonyme und alternative Namen zu Glutamate Dehydrogenase 1

glutamate dehydrogenase 1 (GLUD1), glutamate dehydrogenase 1 (GDH1), glutamate dehydrogenase 1 (glud1), glutamate dehydrogenase 1 S homeolog (glud1.S), glutamate dehydrogenase 1, mitochondrial (LOC693461), glutamate dehydrogenase 1b (glud1b), glutamate dehydrogenase 1 (Glud1), glutamate dehydrogenase (HACJB3_RS00320), glutamate dehydrogenase 1, mitochondrial (LOC100587725), non-compact myelin associated protein (NCMAP), glutamate dehydrogenase (gdh1), glutamate dehydrogenase 1a (glud1a), Ac2-281, AI118167, C2H1orf130, cb622, cb719, GDH, Gdh-X, gdh1, GDH 1, GDH1, Gdh1, GLUD, Glud, glud1, GLUD1, Gludeha, Gludl, GLUTAMATE DECARBOXYLASE 1, GLUTAMATE DEHYDROGENASE 1, glutamate dehydrogenase 1, legdh1, MRG-2, MRG7.13, MRG7_13, wu:fb16e02, wu:fb58f12, wu:fc33g09, wu:fc66a10, wu:fe37f03, wu:fj43f02, zgc:55630, zgc:77186, zgc:192851

Bezeichner auf Proteinebene für Glutamate Dehydrogenase 1

  • GDH 1
  • glutamate dehydrogenase 1, mitochondrial
  • glutamate dehydrogenase 1
  • mitochondrial glutamate dehydrogenase 1
  • glutamate dehydrogenase (NAD(P)+)
  • memory-related gene 2 protein
  • glutamate dehydrogenase 1, mitochondrial-like
  • Legdh1
  • NADH-glutamate dehydrogenase
  • glutamate dehydrogenase
  • glutamate dehydrogenase 1a
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