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Glypican 3 Produkte

(Glypican 3 (GPC3))
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].

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Ausgewählte Glypican 3 Kategorien

Glypican 3 Antikörper

High quality antibodies with extensive validation data.

Glypican 3 ELISA Kits

Reliable ELISA kits for a wide range of species.

Glypican 3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Glypican 3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, FACS, IHC, ELISA, ICC
Validierungen
  • (2)
  • (7)
Kat. Nr. ABIN969523
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, ICC, IP
Validierungen
  • (6)
Kat. Nr. ABIN7442228
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, FACS, IHC, ELISA
Validierungen
  • (6)
Kat. Nr. ABIN7193692
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Glypican 3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (7)
  • (1)
Kat. Nr. ABIN6956276
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (4)
  • (1)
Kat. Nr. ABIN6973977
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6967170
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Glypican 3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7274774
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Cynomolgus
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7274772
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7274775
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Glypican 3 Produkten

Berman, Kelada, Gutsche, Natarajan, Swenson, Fu, Hong, Ho, Choyke, Escorcia: "In Vitro Performance of Published Glypican 3-Targeting Peptides TJ12P1 and L5 Indicates Lack of Specificity and Potency." in: Cancer biotherapy & radiopharmaceuticals, (2019) (PubMed).

Ma, Wang, Liu, Chen, Wu, Li, Mi, Hu, Chen, Zhao: "Development and in vitro study of a bi-specific magnetic resonance imaging molecular probe for hepatocellular carcinoma." in: World journal of gastroenterology, Vol. 25, Issue 24, pp. 3030-3043, (2019) (PubMed).

Fisher, Linder, Bentzer: "Elevated plasma glypicans are associated with organ failure in patients with infection." in: Intensive care medicine experimental, Vol. 7, Issue 1, pp. 2, (2019) (PubMed).

Zhou, Shang, Yu, Tian: "Glypican-3: A promising biomarker for hepatocellular carcinoma diagnosis and treatment." in: Medicinal research reviews, Vol. 38, Issue 2, pp. 741-767, (2018) (PubMed).

Han, Ma, Zhao, Zhao, Batista, Zhou, Zhou, Yang, Wang, Bi, Xia, Bai, Garkavtsev, Zhang: "Identification of Glypican-3 as a potential metastasis suppressor gene in gastric cancer." in: Oncotarget, Vol. 7, Issue 28, pp. 44406-44416, (2018) (PubMed).

Hu, Cheng, He, Wei, Wu, Meng: "Autophagy suppresses proliferation of HepG2 cells via inhibiting glypican-3/wnt/β-catenin signaling." in: OncoTargets and therapy, Vol. 11, pp. 193-200, (2018) (PubMed).

DAvola, Villacorta-Martin, Martins-Filho, Craig, Labgaa, von Felden, Kimaada, Bonaccorso, Tabrizian, Hartmann, Sebra, Schwartz, Villanueva: "High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma." in: Scientific reports, Vol. 8, Issue 1, pp. 11570, (2018) (PubMed).

Wang, Chen, Chen, Sun, Li, Liu: "Elevated GPC3 level promotes cell proliferation in liver cancer." in: Oncology letters, Vol. 16, Issue 1, pp. 970-976, (2018) (PubMed).

Alyoussef, Al-Gayyar: "Cytotoxic and partial hepatoprotective activity of sodium ascorbate against hepatocellular carcinoma through inhibition of sulfatase-2 in vivo and in vitro." in: Biomedicine & pharmacotherapy, Vol. 103, pp. 362-372, (2018) (PubMed).

Cartier, Indersie, Lesjean, Charpentier, Hooks, Ghousein, Desplat, Dugot-Senant, Trézéguet, Sagliocco, Hagedorn, Grosset: "New tumor suppressor microRNAs target glypican-3 in human liver cancer." in: Oncotarget, Vol. 8, Issue 25, pp. 41211-41226, (2017) (PubMed).

Synonyme und alternative Namen zu Glypican 3

glypican 3 (gpc3), glypican 3 (GPC3), glypican 3 (Gpc3), dgsx, DGSX, Glypican-3, GPC3, GTR2-2, MXR7, oci-5, OCI-5, sdys, SDYS, sgb, SGB, sgbs, SGBS, sgbs1, SGBS1

Bezeichner auf Proteinebene für Glypican 3

  • glypican 3
  • glypican-3-like
  • glypican proteoglycan 3
  • glypican-3
  • heparan sulphate proteoglycan
  • intestinal protein OCI-5
  • secreted glypican-3
  • defective in Simpson-Golabi-Behmel overgrowth syndrome
  • proteoglycan GPC3
  • Intestinal protein OCI-5
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