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GNRHR Produkte

(Gonadotropin-Releasing Hormone Receptor (GNRHR))
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte GNRHR Kategorien

GNRHR Antikörper

High quality antibodies with extensive validation data.

GNRHR ELISA Kits

Reliable ELISA kits for a wide range of species.

GNRHR Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene GNRHR Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Rat
Applikation WB, ELISA, IHC (p), IHC (fro), ICC, IF (cc), IF (p)
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN686917
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7242191
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, FACS, IHC (fro)
Validierungen
  • (4)
Kat. Nr. ABIN966217
Menge 0.5 mL
Datenblatt Datenblatt

Empfohlene GNRHR ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6967187
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6967186
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6967185
Menge 96 tests
Datenblatt Datenblatt

Empfohlene GNRHR Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN6964191
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7394573
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
Kat. Nr. ABIN1330111
Menge 2 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren GNRHR Produkten

Baek, Park, Park, Kim, Kim, Suh, Kim, Kim, Kim, Nam: "Androgen receptor as a prognostic biomarker and therapeutic target in uterine leiomyosarcoma." in: Journal of gynecologic oncology, Vol. 29, Issue 3, pp. e30, (2019) (PubMed).

Ciechanowska, Łapot, Paruszewska, Radawiec, Przekop et al.: "The influence of dopaminergic system inhibition on biosynthesis of gonadotrophin-releasing hormone (GnRH) and GnRH receptor in anoestrous sheep; hierarchical role of kisspeptin and RFamide-related ..." in: Reproduction, fertility, and development, (2018) (PubMed).

Park, Baek, Park, Kim, Nam: "Investigation of hormone receptor expression and its prognostic value in endometrial stromal sarcoma." in: Virchows Archiv : an international journal of pathology, Vol. 473, Issue 1, pp. 61-69, (2018) (PubMed).

López-Doval, Salgado, Lafuente: "The expression of several reproductive hormone receptors can be modified by perfluorooctane sulfonate (PFOS) in adult male rats." in: Chemosphere, Vol. 155, pp. 488-97, (2016) (PubMed).

Liu, Li, Zhu, Yu, Guo, Zhou, Zheng, Qu, Huang, Chen, Wang, Ye: "Effects of di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-ovarian axis in adult female rats." in: Reproductive toxicology (Elmsford, N.Y.), Vol. 46, pp. 141-7, (2014) (PubMed).

Benz, Le Hir, Norez, Kerbiriou, Calvez, Becq, Trouvé, Férec: "Improvement of chloride transport defect by gonadotropin-releasing hormone (GnRH) in cystic fibrosis epithelial cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e88964, (2014) (PubMed).

Ko, Guo, Barengo, Naora: "Inhibition of ovarian cancer growth by a tumor-targeting peptide that binds eukaryotic translation initiation factor 4E." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 13, pp. 4336-47, (2009) (PubMed).

Yeung, An, Cheng, Chow, Leung: "Expression and transcriptional regulation of the GnRH receptor gene in human neuronal cells." in: Molecular human reproduction, Vol. 11, Issue 11, pp. 837-42, (2006) (PubMed).

Cheng, Yeung, Chow, Leung: "Characterization of a new upstream GnRH receptor promoter in human ovarian granulosa-luteal cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 7, pp. 1552-64, (2002) (PubMed).

Wolfahrt, Kleine, Jarry, Rossmanith: "Endogenous regulation of the GnRH receptor by GnRH in the human placenta." in: Molecular human reproduction, Vol. 7, Issue 1, pp. 89-95, (2001) (PubMed).

Synonyme und alternative Namen zu GNRHR

gonadotropin releasing hormone receptor (GNRHR), gonadotropin releasing hormone receptor (Gnrhr), gonadotropin releasing hormone receptor (gnrhr), gonadotropin-releasing hormone receptor (gnrh-r), GH1, gnrh-r, GNRHR, GNRHR1, GNRHR1/III, GNRHR2, gnrhr3/ii, GRHR, HH7, LHRHR, Lhrhr, LRHR, xgnrhr

Bezeichner auf Proteinebene für GNRHR

  • gnRH receptor
  • gnRH-R
  • gonadotropin-releasing hormone (type 1) receptor 1
  • leutinizing hormone releasing horomone receptor
  • leutinizing-releasing hormone receptor
  • luliberin receptor
  • type I GnRH receptor
  • GnRH receptor
  • gonadotropin-releasing hormone receptor
  • gonadotropin releasing hormone receptor
  • growth hormone
  • luteinizing-releasing hormone receptor
  • gnoadotropin releasing hormone receptor 2
  • gonadotropin-releasing hormone II receptor
  • type 1/III gonadotropin-releasing hormone receptor hexahelical
  • type 3/II gonadotropin-releasing hormone receptor
  • pituitary GnRH receptor
  • pituitary gonadotropin-releasing hormone receptor
  • LHRH
  • luteinizing hormone-releasing hormone receptor
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