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GPX4 Produkte

(Glutathione Peroxidase 4 (GPX4))
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists\; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq, Jul 2008].

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Ausgewählte GPX4 Kategorien

GPX4 Antikörper

High quality antibodies with extensive validation data.

GPX4 ELISA Kits

Reliable ELISA kits for a wide range of species.

GPX4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene GPX4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, IF
Validierungen
  • (1)
  • (8)
Kat. Nr. ABIN3015730
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (9)
Kat. Nr. ABIN7438652
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7439558
Menge 100 μL
Datenblatt Datenblatt

Empfohlene GPX4 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6975523
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6975657
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956199
Menge 96 tests
Datenblatt Datenblatt

Empfohlene GPX4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123131
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7403591
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7404995
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren GPX4 Produkten

Wang, Zheng, Zhang, Zhao, Wang, Wang, Shang, Barasch, Qiu: "Physiological functions of ferroportin in the regulation of renal iron recycling and ischemic acute kidney injury." in: American journal of physiology. Renal physiology, Vol. 315, Issue 4, pp. F1042-F1057, (2018) (PubMed).

Agbor, Demma, Mrsny, Castillo, Boll, McCormick: "The oxido-reductase enzyme glutathione peroxidase 4 (GPX4) governs Salmonella Typhimurium-induced neutrophil transepithelial migration." in: Cellular microbiology, Vol. 16, Issue 9, pp. 1339-53, (2014) (PubMed).

Papp, Lu, Bolderson, Boucher, Singh, Holmgren, Khanna: "SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress." in: Antioxidants & redox signaling, Vol. 12, Issue 7, pp. 797-808, (2010) (PubMed).

Schoenmakers, Agostini, Mitchell, Schoenmakers, Papp, Rajanayagam, Padidela, Ceron-Gutierrez, Doffinger, Prevosto, Luan, Montano, Lu, Castanet, Clemons, Groeneveld, Castets, Karbaschi, Aitken, Dixon et al.: "Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. ..." in: The Journal of clinical investigation, Vol. 120, Issue 12, pp. 4220-35, (2010) (PubMed).

Blackinton, Kumaran, van der Brug, Ahmad, Olson, Galter, Lees, Bandopadhyay, Cookson: "Post-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson disease." in: Neuroscience letters, Vol. 452, Issue 1, pp. 8-11, (2009) (PubMed).

Su, Novoselov, Sun, Moustafa, Zhou, Oko, Hatfield, Gladyshev: "Mammalian selenoprotein thioredoxin-glutathione reductase. Roles in disulfide bond formation and sperm maturation." in: The Journal of biological chemistry, Vol. 280, Issue 28, pp. 26491-8, (2005) (PubMed).

Nakagawa: "Role of mitochondrial phospholipid hydroperoxide glutathione peroxidase (PHGPx) as an antiapoptotic factor." in: Biological & pharmaceutical bulletin, Vol. 27, Issue 7, pp. 956-60, (2004) (PubMed).

Takebe, Yarimizu, Saito, Hayashi, Nakamura, Yodoi, Nagasawa, Takahashi: "A comparative study on the hydroperoxide and thiol specificity of the glutathione peroxidase family and selenoprotein P." in: The Journal of biological chemistry, Vol. 277, Issue 43, pp. 41254-8, (2002) (PubMed).

Synonyme und alternative Namen zu GPX4

glutathione peroxidase 4 (GPX4), glutathione peroxidase 4 (Gpx4), glutathione peroxidase 4a (gpx4a), 1700027O09Rik, ATGPX4, cb563, cb691, F11L15.5, glutathione peroxidase 4, GP-GPx4, GPx-4, gpx-4, GSHPx-4, MCSP, mtPHGPx, PHGPx, Phgpx, PHGPxa, sb:cb563, snGPx, snGpx, snPHGPx, wu:fb82e03, zgc:92253

Bezeichner auf Proteinebene für GPX4

  • phospholipid hydroperoxidase
  • phospholipid hydroperoxide glutathione peroxidase, mitochondrial
  • sperm nucleus glutathione peroxidase
  • GSHPx-4
  • phospholipid hydroperoxide glutathione peroxidase, nuclear
  • glutathione peroxidase 4
  • GPx-4
  • sperm nuclei glutathione peroxidase
  • glutathione peroxidase 4 (phospholipid hydroperoxidase)
  • phospholipid hydroperoxide glutathione peroxidase
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