GRB10 Produkte
(Growth Factor Receptor-Bound Protein 10 (GRB10))
Kategorien
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010].
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Ausgewählte GRB10 Kategorien
GRB10 Antikörper
High quality antibodies with extensive validation data.
GRB10 ELISA Kits
Reliable ELISA kits for a wide range of species.
GRB10 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GRB10 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), ICC, IHC (fro)
Validierungen
- (7)
Kat. Nr.
ABIN7436048
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN561124
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN3184930
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene GRB10 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967246
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956335
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380446
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene GRB10 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1355698
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1355696
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7398446
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GRB10 Produkten
: "Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases." in: The Journal of biological chemistry, Vol. 273, Issue 17, pp. 10475-84, (1998) (PubMed).: "Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains." in: The Journal of biological chemistry, Vol. 272, Issue 5, pp. 2659-67, (1997) (PubMed).
: "Cloning, chromosome localization, expression, and characterization of an Src homology 2 and pleckstrin homology domain-containing insulin receptor binding protein hGrb10gamma." in: The Journal of biological chemistry, Vol. 272, Issue 46, pp. 29104-12, (1997) (PubMed).
: "Interaction of a GRB-IR splice variant (a human GRB10 homolog) with the insulin and insulin-like growth factor I receptors. Evidence for a role in mitogenic signaling." in: The Journal of biological chemistry, Vol. 271, Issue 37, pp. 22506-13, (1996) (PubMed).
: "Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 22, pp. 10287-91, (1995) (PubMed).
Synonyme und alternative Namen zu GRB10
growth factor receptor bound protein 10 (GRB10), growth factor receptor-bound protein 10a (grb10a), growth factor receptor bound protein 10 (grb10), growth factor receptor bound protein 10 L homeolog (grb10.L), growth factor receptor-bound protein 10 (LOC100434903), growth factor receptor bound protein 10 (Grb10), 5730571D09Rik, AI325020, grb-10, Grb-10, grb-ir, GRB-IR, grb10, GRB10, irbp, IRBP, LOC100224775, meg1, Meg1, MEG1, mKIAA0207, RGD1566234, rss, RSS, zgc:91987Bezeichner auf Proteinebene für GRB10
- growth factor receptor-bound protein 10
- zgc:91987growth factor receptor-bound protein 10
- growth factor receptor-bound protein 10-like
- GRB10 adapter protein
- maternally expressed gene 1 protein
- GRB10 adaptor protein
- insulin receptor-binding protein Grb-IR
- maternally expressed gene 1
- adapter protein
- binds to insulin receptor and IGF1R
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