GRID2 Produkte
(Glutamate Receptor, Ionotropic, delta 2 (GRID2))
Kategorien
Human glutamate receptor delta-2 (GRID2) is a relatively new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. GRID2 is a predicted 1,007 amino acid protein that shares 97% identity with the mouse homolog which is expressed selectively in cerebellar Purkinje cells. A point mutation in mouse GRID2, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This strongly suggests a role for GRID2 in neuronal apoptotic death. [provided by RefSeq, Jul 2008].
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Ausgewählte GRID2 Kategorien
GRID2 Antikörper
High quality antibodies with extensive validation data.
GRID2 ELISA Kits
Reliable ELISA kits for a wide range of species.
GRID2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GRID2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IF, ELISA, ICC, IHC
Validierungen
- (3)
Kat. Nr.
ABIN6257247
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN561131
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, ELISA
Validierungen
- (1)
Kat. Nr.
ABIN7184958
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene GRID2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956153
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1503169
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1503171
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene GRID2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1355734
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GRID2 Produkten
: "Differential localization of delta glutamate receptors in the rat cerebellum: coexpression with AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 17, Issue 2, pp. 834-42, (1997) (PubMed).: "Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene." in: Nature, Vol. 388, Issue 6644, pp. 769-73, (1997) (PubMed).
: "Suppression of LTD in cultured Purkinje cells deficient in the glutamate receptor delta 2 subunit." in: Neuroreport, Vol. 6, Issue 3, pp. 524-6, (1995) (PubMed).
: "Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice." in: Cell, Vol. 81, Issue 2, pp. 245-52, (1995) (PubMed).
: "Selective expression of the glutamate receptor channel delta 2 subunit in cerebellar Purkinje cells." in: Biochemical and biophysical research communications, Vol. 197, Issue 3, pp. 1267-76, (1994) (PubMed).
Synonyme und alternative Namen zu GRID2
glutamate receptor, ionotropic, delta 2 (grid2), glutamate receptor ionotropic, delta-2 (LOC704787), glutamate ionotropic receptor delta type subunit 2 (GRID2), glutamate receptor, ionotropic, delta 2 (Grid2), glutamate ionotropic receptor delta type subunit 2 (Grid2), glutamate receptor ionotropic, delta-2 (LOC536367), B230104L07Rik, cpr, GluD2, glurd2, GluRdelta2, GRID2, ho, Lc, LcBezeichner auf Proteinebene für GRID2
- gluR delta-2 subunit
- glutamate receptor delta-2 subunit
- glutamate receptor ionotropic, delta-2
- glutamate receptor, ionotropic, delta 2
- glutamate receptor delta-2 subunit-like
- GluR-delta-2
- creeper
- hotfoot
- lurcher
- minisatellite 10ac detected by probe MMS10
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