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GRIN1/NMDAR1 Produkte

(Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].

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Ausgewählte GRIN1/NMDAR1 Kategorien

GRIN1/NMDAR1 Antikörper

High quality antibodies with extensive validation data.

GRIN1/NMDAR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

GRIN1/NMDAR1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene GRIN1/NMDAR1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
anti-GRIN1/NMDAR1 Antikörper (AA 600-700)
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN6141400
Menge 100 μL
Datenblatt Datenblatt
anti-GRIN1/NMDAR1 Antikörper (Internal Region)
Reaktivität Human, Mouse
Applikation ELISA, IF
Validierungen
  • (5)
Kat. Nr. ABIN185678
Menge 100 μg
Datenblatt Datenblatt
anti-GRIN1/NMDAR1 Antikörper (C-Term)
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, ELISA, IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN6263664
Menge 100 μL
Datenblatt Datenblatt

Empfohlene GRIN1/NMDAR1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
GRIN1/NMDAR1 ELISA Kit
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6967062
Menge 96 tests
Datenblatt Datenblatt
GRIN1/NMDAR1 ELISA Kit
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6967061
Menge 96 tests
Datenblatt Datenblatt
GRIN1/NMDAR1 ELISA Kit
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6967060
Menge 96 tests
Datenblatt Datenblatt

Empfohlene GRIN1/NMDAR1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
GRIN1/NMDAR1 Protein (AA 21-120) (GST tag)
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1355746
Menge 10 μg
Datenblatt Datenblatt
GRIN1/NMDAR1 Protein (AA 19-559) (His tag)
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7398170
Menge 100 μg
Datenblatt Datenblatt
GRIN1/NMDAR1 Protein (AA 19-559) (His tag)
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7502540
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren GRIN1/NMDAR1 Produkten

Stewart, Lau, Banks, Bains, Castroflorio, Oliver, Dixon, Kruer, Kullmann, Acevedo-Arozena, Wells, Corrochano, Nolan: "Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities." in: Disease models & mechanisms, Vol. 12, Issue 2, (2019) (PubMed).

Shi, Hung, Rocha, Lin, Linares, Staats, Seah, Wang, Chickering, Lai, Sugawara, Sagare, Zlokovic, Ichida: "Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons." in: JCI insight, Vol. 5, (2019) (PubMed).

Shi, Lin, Staats, Li, Chang, Hung, Hendricks, Linares, Wang, Son, Wen, Kisler, Wilkinson, Menendez, Sugawara, Woolwine, Huang, Cowan, Ge, Koutsodendris, Sandor, Komberg, Vangoor, Senthilkumar, Hennes et al.: "Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons. ..." in: Nature medicine, Vol. 24, Issue 3, pp. 313-325, (2018) (PubMed).

Gorska-Ponikowska, Perricone, Kuban-Jankowska, Lo Bosco, Barone: "2-methoxyestradiol impacts on amino acids-mediated metabolic reprogramming in osteosarcoma cells by its interaction with NMDA receptor." in: Journal of cellular physiology, (2017) (PubMed).

Tan, Chen, Wang, Zhang, Li, Zhao, Wang, Luo: "Pharmacological inhibition of PTEN attenuates cognitive deficits caused by neonatal repeated exposures to isoflurane via inhibition of NR2B-mediated tau phosphorylation in rats." in: Neuropharmacology, Vol. 114, pp. 135-145, (2017) (PubMed).

Wang, Li, Liu, Feng, Jiang, Long, Wu: "Motor neuron degeneration following glycine-mediated excitotoxicity induces spastic paralysis after spinal cord ischemia/reperfusion injury in rabbit." in: American journal of translational research, Vol. 9, Issue 7, pp. 3411-3421, (2017) (PubMed).

Hewett, Shi, Gong, Dhandapani, Pilbeam, Hewett et al.: "Spontaneous Glutamatergic Synaptic Activity Regulates Constitutive COX-2 Expression in Neurons: OPPOSING ROLES FOR THE TRANSCRIPTION FACTORS CREB (cAMP RESPONSE ELEMENT BINDING) PROTEIN AND Sp1 ..." in: The Journal of biological chemistry, Vol. 291, Issue 53, pp. 27279-27288, (2016) (PubMed).

Feng, Du: "Mechanisms responsible for the effect of median nerve electrical stimulation on traumatic brain injury-induced coma: orexin-A-mediated N-methyl-D-aspartate receptor subunit NR1 upregulation." in: Neural regeneration research, Vol. 11, Issue 6, pp. 951-6, (2016) (PubMed).

Hanson, Pare, Deng, Smith, Zhou: "Altered GluN2B NMDA receptor function and synaptic plasticity during early pathology in the PS2APP mouse model of Alzheimer's disease." in: Neurobiology of disease, Vol. 74, pp. 254-62, (2015) (PubMed).

Balsara, Dang, Donahue, Snow, Castellino: "Conantokin-G attenuates detrimental effects of NMDAR hyperactivity in an ischemic rat model of stroke." in: PLoS ONE, Vol. 10, Issue 3, pp. e0122840, (2015) (PubMed).

Synonyme und alternative Namen zu GRIN1/NMDAR1

glutamate ionotropic receptor NMDA type subunit 1 (GRIN1), glutamate receptor, ionotropic, N-methyl D-aspartate 1 S homeolog (grin1.S), glutamate ionotropic receptor NMDA type subunit 1 (grin1), glutamate ionotropic receptor NMDA type subunit 1 (Grin1), NMDA receptor 1 (Nmdar1), G protein-regulated inducer of neurite outgrowth 1 (Gprin1), glutamate receptor, ionotropic, NMDA1 (zeta 1) (Grin1), glutamate receptor, ionotropic, N-methyl D-aspartate 1a (grin1a), GB19253, GluN1, GluRdelta1, GluRzeta1, GRIN1, M100174, MRD8, NMD-R1, NMDA1, nmda1, Nmdar, NMDAR1, nmdar1, NMDAR1.1, NR1, Rgsc174, Z16, zgc:152678

Bezeichner auf Proteinebene für GRIN1/NMDAR1

  • N-methyl-D-aspartate receptor channel, subunit zeta-1
  • N-methyl-D-aspartate receptor subunit NR1
  • NMD-R1
  • glutamate [NMDA] receptor subunit zeta 1
  • glutamate [NMDA] receptor subunit zeta-1
  • glutamate receptor ionotropic, NMDA 1
  • N-methyl-D-aspartate receptor
  • NMDA glutamate receptor
  • glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • N-methyl-D-aspartate glutamate receptor
  • NMDA R1 receptor C1 cassette
  • neurotransmitter receptor
  • NMDA-type glutamate receptor 1
  • NMDA-type glutamate receptor subunit 1
  • N-methyl-D-aspartate receptor 1
  • Glutamate [NMDA] receptor subunit zeta-1
  • glutamate receptor subunit zeta 1
  • N-methyl-D-aspartate receptor type 1
  • NMDA receptor glycine-binding subunit NR1.1
  • glutamate receptor, ionotropic, N-methyl D-aspartate 1a
  • round spermatid basic protein 1

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