GUT2 Protein (AA 43-600) (His tag)
GUT2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, ELISA
-
- Target
- GUT2 (Mitochondrial Glycerol-3-Phosphate Dehydrogenase (GUT2))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 43-600
- Spezies
- Human
- Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses GUT2 Protein ist gelabelt mit His tag.
- Applikation
- Western Blotting (WB), ELISA
- Verwendungszweck
- Mitochondrial Glycerol-3-Phosphate Dehydrogenase (mGPD)
- Sequenz
- ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS VQAAEEALPR IVELMGRELN WDDYKKQEQL ETARKFLY
- Produktmerkmale
- recombinant mGPD comprises a 558 amino acid fragment (43-600) corresponding to the GlpA domain fragment of the mature mGPD protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
- Reinheit
- > 95 %
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- 20 mM Tris HCl pH 8, 1 mM EDTA, 50 % Glycerol
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C
-
- Target
- GUT2 (Mitochondrial Glycerol-3-Phosphate Dehydrogenase (GUT2))
- Andere Bezeichnung
- Mitochondrial Glycerol-3-Phosphate Dehydrogenase
- Hintergrund
- Mitochondrial glycerol-3-phosphate dehydrogenase (mGPD) is a Ca2+ -sensitive, FAD-binding protein, located on the outer surface of the inner mitochondrial membrane. mGPD catalyses the oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Two isoforms have been described for mGPD. Isoform 1 comprises 727aa residues, whereas isoform 2 lacks 126aa residues of the N-terminus. Deficiency of mGPD appears to contribute to the impairment of glucose-stimulated insulin release in several animal models of non-insulin dependent diabetes mellitus.,Glycerol-3-Phosphate Dehydrogenase 2, GPD2, Glycerophosphate Dehydrognase-2 Ca(2+ ) - Responsive Mitochondrial FAD-Linked, Mitochondrial GPD, GPDM, GPD-M, GPDH-M, mtGPD, GDH2.
- Molekulargewicht
- 66.26 kDa
- UniProt
- P43304
-
Sie sind hier:
