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HAX1 Produkte

(HCLS1 Associated Protein X-1 (HAX1))
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte HAX1 Kategorien

HAX1 Antikörper

High quality antibodies with extensive validation data.

HAX1 ELISA Kits

Reliable ELISA kits for a wide range of species.

HAX1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene HAX1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), ICC
Validierungen
  • (5)
Kat. Nr. ABIN2855251
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, IF, IP
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN968199
Menge 150 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7154840
Menge 100 μg
Datenblatt Datenblatt

Empfohlene HAX1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1136117
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1136116
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1136118
Menge 96 tests
Datenblatt Datenblatt

Empfohlene HAX1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1306379
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1306381
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN1098543
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren HAX1 Produkten

Gomathinayagam, Muralidharan, Ha, Varadarajalu, Dhanasekaran: "Hax-1 is required for Rac1-Cortactin interaction and ovarian carcinoma cell migration." in: Genes & cancer, Vol. 5, Issue 3-4, pp. 84-99, (2014) (PubMed).

Chao, Parganas, Boyd, Hong, Opferman, Ihle: "Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons." in: Nature, Vol. 452, Issue 7183, pp. 98-102, (2008) (PubMed).

Suzuki, Demoliere, Kitamura, Takeshita, Deuschle, Watanabe: "HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 6, pp. 2736-44, (1997) (PubMed).

Synonyme und alternative Namen zu HAX1

HCLS1 associated protein X-1 (HAX1), HCLS1 associated protein X-1 (hax1), HCLS1 associated protein X-1 (Hax1), HCLS1 associated X-1 (Hax1), HAX-1, HAX1, hax1, HCLSBP1, HS1BP1, Hs1bp1, HSP1BP-1, mHAX-1s, SCN3, SIG-111, Silg111

Bezeichner auf Proteinebene für HAX1

  • HCLS1 associated protein X-1
  • HCLS1-associated protein X-1
  • HAX-1
  • HCLS1 (and PKD2) associated protein
  • HS1 binding protein
  • HS1-associating protein X-1
  • HS1-binding protein 1
  • HSP1BP-1
  • HS1-associated protein X-1
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