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HBEGF Produkte

(Heparin-Binding EGF-Like Growth Factor (HBEGF))
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

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Ausgewählte HBEGF Kategorien

HBEGF Antikörper

High quality antibodies with extensive validation data.

HBEGF ELISA Kits

Reliable ELISA kits for a wide range of species.

HBEGF Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene HBEGF Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation ELISA, IF (cc), IHC (p)
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN701050
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7433663
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IP, ICC, IF
Validierungen
  • (4)
  • (4)
Kat. Nr. ABIN2451994
Menge 50 μg
Datenblatt Datenblatt

Empfohlene HBEGF ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6956482
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6956483
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6956484
Menge 96 tests
Datenblatt Datenblatt

Empfohlene HBEGF Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123301
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN7092863
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN7092865
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren HBEGF Produkten

Lee, Kim: "Eckol Alleviates Intestinal Dysfunction during Suckling-to-Weaning Transition via Modulation of PDX1 and HBEGF." in: International journal of molecular sciences, Vol. 21, Issue 13, (2020) (PubMed).

Wang, Zhang, Li, Mao, Sun, Chen, Zhang, Bartsch, Shu, Lei: "ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway." in: Biomedicine & pharmacotherapy, Vol. 97, pp. 1066-1077, (2018) (PubMed).

Nawaz, Aminuddin, Kado, Takikawa, Yamamoto, Tsuneyama, Igarashi, Ikutani, Nishida, Nagai, Takatsu, Imura, Sasahara, Okazaki, Ueki, Okamura, Tokuyama, Ando, Matsumoto, Mori, Nakagawa, Kobayashi, Saeki et al.: "CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors. ..." in: Nature communications, Vol. 8, Issue 1, pp. 286, (2018) (PubMed).

Lai, Li, Chen, Pan, Wen, Mai, Yuan, Lv, Lv, Cen, Yi, Wen, Li, Wu, Wu, Cao: "Heparin-binding epidermal growth factor contributes to COPD disease severity by modulating airway fibrosis and pulmonary epithelial-mesenchymal transition." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 98, Issue 9, pp. 1159-1169, (2018) (PubMed).

Lim, Yoo, Kim, Hur, Lee, Hur, Lee, Lee, Park, Lee, Chang, Kim, Kang, Hong, Kim, Kim, Yoon, Nam, Yang, Kim, Cho, Won: "GC1118, an Anti-EGFR Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity against High-Affinity EGFR Ligands." in: Molecular cancer therapeutics, Vol. 15, Issue 2, pp. 251-63, (2016) (PubMed).

Lebkuechner, Wilhelmsson, Möllerström, Pekna, Pekny: "Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency." in: Journal of neurochemistry, (2015) (PubMed).

Fujita, Kasai, Omachi, Sakaguchi, Shinohara: "A novel method for assessing bladder-related pain reveals the involvement of nerve growth factor in pain associated with cyclophosphamide-induced chronic cystitis in mice." in: European journal of pain (London, England), Vol. 20, Issue 1, pp. 79-91, (2015) (PubMed).

Mandl, Drechsler, Jansen, Neideck, Noels, Faussner, Soehnlein, Weber, Döring: "Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation." in: PLoS ONE, Vol. 10, Issue 8, pp. e0134176, (2015) (PubMed).

David, Sahay, Mege, Descotes, Leblanc, Ribeiro, Clézardin, Peyruchaud: "Identification of heparin-binding EGF-like growth factor (HB-EGF) as a biomarker for lysophosphatidic acid receptor type 1 (LPA1) activation in human breast and prostate cancers." in: PLoS ONE, Vol. 9, Issue 5, pp. e97771, (2015) (PubMed).

Palazuelos, Crawford, Klingener, Sun, Karelis, Raines, Aguirre: "TACE/ADAM17 is essential for oligodendrocyte development and CNS myelination." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 36, pp. 11884-96, (2014) (PubMed).

Synonyme und alternative Namen zu HBEGF

heparin-binding EGF-like growth factor b (hbegfb), heparin binding EGF like growth factor (HBEGF), Heparin-binding EGF-like growth factor (hbegf), heparin-binding EGF-like growth factor a (hbegfa), heparin-binding EGF-like growth factor (Hbegf), AW047313, DTR, Dtr, DTS, Dts, DTSF, GFHB, Hb-egf, HB-EGF, hbegf, HBEGF, HEGFL, Hegfl, zgc:165443, zgc:175091

Bezeichner auf Proteinebene für HBEGF

  • proheparin-binding EGF-like growth factor
  • heparin-binding EGF-like growth factor
  • Heparin-binding EGF-like growth factor
  • diphtheria toxin receptor (heparin-binding EGF-like growth factor)
  • diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor)
  • heparin-binding epidermal growth factor
  • Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor)
  • heparin binding epidermal growth factor-like growth factor
  • heparin-binding epidermal -growth - like growth factor
  • heparin-binding epidermal -growth factor
  • diphtheria toxin receptor
  • heparin-binding epidermal growth factor-like growth factor
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