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HDAC4 Produkte

(Histone Deacetylase 4 (HDAC4))

Kategorien

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

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Ausgewählte HDAC4 Kategorien

HDAC4 Antikörper

High quality antibodies with extensive validation data.

HDAC4 ELISA Kits

Reliable ELISA kits for a wide range of species.

HDAC4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene HDAC4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7441235
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, FACS
Validierungen
  • (5)
Kat. Nr. ABIN5542325
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC (p)
Validierungen
  • (5)
Kat. Nr. ABIN523212
Menge 100 μg
Datenblatt Datenblatt

Empfohlene HDAC4 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956574
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956575
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380595
Menge 2 x 96 tests
Datenblatt Datenblatt

Empfohlene HDAC4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1306452
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1306454
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN2722509
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren HDAC4 Produkten

Karppinen, Hänninen, Rapila, Tavi: "Sarcoplasmic reticulum Ca2+ -induced Ca2+ release regulates class IIa HDAC localization in mouse embryonic cardiomyocytes." in: Physiological reports, Vol. 6, Issue 2, (2019) (PubMed).

Sirchia, Faversani, Rovina, Russo, Paganini, Savi, Augello, Rosso, Del Gobbo, Tabano, Bosari, Miozzo: "Epigenetic effects of chromatin remodeling agents on organotypic cultures." in: Epigenomics, Vol. 8, Issue 3, pp. 341-58, (2016) (PubMed).

Trazzi, Fuchs, Viggiano, De Franceschi, Valli, Jedynak, Hansen, Perini, Rimondini, Kurz, Bartesaghi, Ciani: "HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder." in: Human molecular genetics, Vol. 25, Issue 18, pp. 3887-3907, (2016) (PubMed).

Liu, Gu, Feng, Yang, Zhu, Lu, Qi: "Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells." in: Journal of translational medicine, Vol. 14, pp. 7, (2016) (PubMed).

Yang, Li, Chen, Yuan, Dong, Zhang, Wu, Wang: "PARP-1 mediates LPS-induced HMGB1 release by macrophages through regulation of HMGB1 acetylation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 12, pp. 6114-23, (2014) (PubMed).

Isaacs, Antony, Dalrymple, Brennen, Gerber, Hammers, Wissing, Kachhap, Luo, Xing, Björk, Olsson, Björk, Leanderson: "Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment." in: Cancer research, Vol. 73, Issue 4, pp. 1386-99, (2013) (PubMed).

Cao, Li, Zhu, Shen, Han, Zhang, Yu, Wang, Wu, Chen, Sun, Tang, Zhao, Qiao, Hou, Mao: "The antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 34181-9, (2013) (PubMed).

Abu-Farha, Tiss, Abubaker, Khadir, Al-Ghimlas, Al-Khairi, Baturcam, Cherian, Elkum, Hammad, John, Kavalakatt, Warsame, Behbehani, Dermime, Dehbi: "Proteomics analysis of human obesity reveals the epigenetic factor HDAC4 as a potential target for obesity." in: PLoS ONE, Vol. 8, Issue 9, pp. e75342, (2013) (PubMed).

Mielcarek, Landles, Weiss, Bradaia, Seredenina, Inuabasi, Osborne, Wadel, Touller, Butler, Robertson, Franklin, Smith, Park, Marks, Wanker, Olson, Luthi-Carter, van der Putten, Beaumont, Bates: "HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration." in: PLoS biology, Vol. 11, Issue 11, pp. e1001717, (2013) (PubMed).

Kornfeld, Biggar, Storey: "Differential expression of mature microRNAs involved in muscle maintenance of hibernating little brown bats, Myotis lucifugus: a model of muscle atrophy resistance." in: Genomics, proteomics & bioinformatics, Vol. 10, Issue 5, pp. 295-301, (2012) (PubMed).

Synonyme und alternative Namen zu HDAC4

histone deacetylase 4 (PTRG_03699), hypothetical protein (PGTG_15512), Histone deacetylase 4 (HDAC4), GF18710 gene product from transcript GF18710-RC (Dana\GF18710), histone deacetylase 4 (HDAC4), histone deacetylase 4 (Hdac4), histone deacetylase 4 (hdac4), 4932408F19Rik, AHO3, AI047285, BDMR, CG1770, DanaGF18710, dana_GLEANR_19966, DHDAC4, dHDAC4, Dmel\\CG1770, dmHDA405, GC1770, GF18710, HA6116, HD4, HDAC, HDAC-4, HDAC-A, hdac4, HDAC4, HDAC4a, HDACA, wu:fa96d08, wu:fc56f08, zgc:152701

Bezeichner auf Proteinebene für HDAC4

  • histone deacetylase 4
  • CG1770-PB
  • CG1770-PD
  • CG1770-PE
  • CG1770-PF
  • CG1770-PG
  • CG1770-PH
  • CG1770-PI
  • CG1770-PJ
  • HDAC4-PB
  • HDAC4-PD
  • HDAC4-PE
  • HDAC4-PF
  • HDAC4-PG
  • HDAC4-PH
  • HDAC4-PI
  • HDAC4-PJ
  • DanaGF18710-PA
  • DanaHDAC4-PA
  • GF18710-PA
  • HDAC4
  • HDAC4-PA
  • histone deacetylase A
  • HD4
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