HDAC8 Produkte
(Histone Deacetylase 8 (HDAC8))
Kategorien
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
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Ausgewählte HDAC8 Kategorien
HDAC8 Antikörper
High quality antibodies with extensive validation data.
HDAC8 ELISA Kits
Reliable ELISA kits for a wide range of species.
HDAC8 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene HDAC8 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF, IP
Validierungen
- (7)
Kat. Nr.
ABIN7267714
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IF
Validierungen
- (5)
Kat. Nr.
ABIN527747
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IP
Validierungen
- (4)
Kat. Nr.
ABIN527748
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene HDAC8 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967441
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380597
Menge
2 x 96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6951139
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene HDAC8 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1306466
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1306464
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Baculovirus infected Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN7320338
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HDAC8 Produkten
: "HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy." in: Cancer research, Vol. 79, Issue 11, pp. 2947-2961, (2019) (PubMed).: "Regulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by the Histone Deacetylase 6." in: EBioMedicine, Vol. 9, pp. 195-206, (2017) (PubMed).
: "HDAC8 and STAT3 repress BMF gene activity in colon cancer cells." in: Cell death & disease, Vol. 5, pp. e1476, (2014) (PubMed).
: "The tricyclic antidepressant amitriptyline inhibits D-cyclin transactivation and induces myeloma cell apoptosis by inhibiting histone deacetylases: in vitro and in silico evidence." in: Molecular pharmacology, Vol. 79, Issue 4, pp. 672-80, (2011) (PubMed).
: "Histone deacetylase inhibitors stimulate histone H3 lysine 4 methylation in part via transcriptional repression of histone H3 lysine 4 demethylases." in: Molecular pharmacology, Vol. 79, Issue 1, pp. 197-206, (2010) (PubMed).
: "Negative regulation of histone deacetylase 8 activity by cyclic AMP-dependent protein kinase A." in: Molecular and cellular biology, Vol. 24, Issue 2, pp. 765-73, (2003) (PubMed).
: "Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor." in: The Journal of biological chemistry, Vol. 275, Issue 20, pp. 15254-64, (2000) (PubMed).
: "Characterization of a highly complex region in Xq13 and mapping of three isodicentric breakpoints associated with preleukemia." in: Genomics, Vol. 64, Issue 3, pp. 221-9, (2000) (PubMed).
: "Cloning and characterization of human histone deacetylase 8." in: FEBS letters, Vol. 478, Issue 1-2, pp. 77-83, (2000) (PubMed).
Synonyme und alternative Namen zu HDAC8
histone deacetylase 8 (CC1G_05302), histone deacetylase 8 (hdac8), histone deacetylase 8 (HDAC8), histone deacetylase 8 (Hdac8), histone deacetylase 8 L homeolog (hdac8.L), histone deacetylase 8 (HDA08), 2610007D20Rik, ATHDA8, CDLS5, HD8, HDA8, HDACL1, HISTONE DEACETYLASE 8, histone deacetylase 8, MRXS6, RGD1562895, RPD3, T27G7.14, T27G7_14, WTS, wu:fd19a02, zgc:66196Bezeichner auf Proteinebene für HDAC8
- histone deacetylase 8
- histone deacetylase-like 1
- HD8
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