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Heat Shock Protein 65 (HSP65) Antikörper

HSP65 Reaktivität: Mykobakterien EIA, WB Wirt: Maus Monoclonal BDI578 unconjugated
Produktnummer ABIN2859572
  • Target Alle Heat Shock Protein 65 (HSP65) Produkte
    Heat Shock Protein 65 (HSP65)
    Reaktivität
    Mykobakterien
    Wirt
    Maus
    Klonalität
    Monoklonal
    Applikation
    Enzyme Immunoassay (EIA), Western Blotting (WB)
    Spezifität
    This antibody is reactive with Hsp65 (GroEL) of M. tuberculosis. Does not react with M. bovis, M. avium, M. phlei, M. parafortuitum, Rhodococcus sp., B. subtilis, S. pneumoniae, and E. coli.
    Produktmerkmale
    Synonyms: 60 kDa chaperonin 2, Protein Cpn60-2, groEL protein 2, Cell wall protein A, Antigen A,groL2, groEL-2, groEL2, hsp65, Rv0440, MT0456, MTV037.04
    Aufreinigung
    Protein A chromatography
    Reinheit
    > 90 % pure
    Immunogen
    Purified protein derivative (PPD)
    Klon
    BDI578
    Isotyp
    IgG2a
  • Applikationshinweise
    ELISA. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0,1 mg/mL (OD280nm, E0.1% = 1.4)
    Buffer
    0.01 M PBS, pH 7.2 containing 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    Heat Shock Protein 65 (HSP65)
    Andere Bezeichnung
    Heat Shock Protein 65 / HSP65
    Synonyme
    CPN60 antikoerper, GROEL antikoerper, HLD4 antikoerper, HSP-60 antikoerper, HSP60 antikoerper, HSP65 antikoerper, HuCHA60 antikoerper, SPG13 antikoerper, heat shock protein family D (Hsp60) member 1 antikoerper, HSPD1 antikoerper
    Hintergrund
    Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure, most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.Synonyms: 60 kDa chaperonin 2, Antigen A, Cell wall protein A, MT0456, MTV037.04, Protein Cpn60-2, Rv0440, groEL protein 2, groEL-2, groEL2, groL2, hsp65
    Gen-ID
    886354
    UniProt
    P0A520
    Pathways
    Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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