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HFE2 Produkte

(Hemochromatosis Type 2 (Juvenile) (HFE2))

Kategorien

The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30. [provided by RefSeq, Jul 2008].

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Ausgewählte HFE2 Kategorien

HFE2 Antikörper

High quality antibodies with extensive validation data.

HFE2 ELISA Kits

Reliable ELISA kits for a wide range of species.

HFE2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene HFE2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7441934
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN566853
Menge 50 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN530965
Menge 100 μg
Datenblatt Datenblatt

Empfohlene HFE2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (11)
  • (1)
Kat. Nr. ABIN6956455
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6956456
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Competition ELISA
Validierungen
  • (4)
  • (1)
Kat. Nr. ABIN6956454
Menge 96 tests
Datenblatt Datenblatt

Empfohlene HFE2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1306581
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Synthetic
Validierungen
  • (2)
Kat. Nr. ABIN1880255
Menge 200 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7413832
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren HFE2 Produkten

Young, Tang, Wu, Wang, Nong, Huang, Hu, Chiou, Jeng, Hsu: "The functional role of hemojuvelin in acute ischemic stroke." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 40, Issue 6, pp. 1316-1327, (2021) (PubMed).

Ko, Chi, Wu, Huang, Chueh, Wang, Lin, Wang, Ting, Chang, Connolly, Lai, Tseng, Wu, Chu: "Hemojuvelin Predicts Acute Kidney Injury and Poor Outcomes Following Cardiac Surgery." in: Scientific reports, Vol. 8, Issue 1, pp. 1938, (2018) (PubMed).

Wang, Chi, Huang, Connolly, Chen, Chueh, Kan, Lai, Wu, Fang, Chu, Wu: "Urinary biomarkers predict advanced acute kidney injury after cardiovascular surgery." in: Critical care, Vol. 22, Issue 1, pp. 108, (2018) (PubMed).

Ferro, Di Pietro, Visalli, Piraino, Salpietro, La Rosa: "Soluble hemojuvelin in transfused and untransfused thalassaemic subjects." in: European journal of haematology, Vol. 98, Issue 1, pp. 67-74, (2017) (PubMed).

Cyranoski: "The secret war against counterfeit science." in: Nature, Vol. 545, Issue 7653, pp. 148-150, (2017) (PubMed).

S?omka, ?wito?ska, ?ekanowska: "Hepcidin Levels Are Increased in Patients with Acute Ischemic Stroke: Preliminary Report." in: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 24, Issue 7, pp. 1570-6, (2015) (PubMed).

Jankowska, Wojtas, Kasztura, Mazur, Butrym, Kalicinska, Rybinska, Skiba, von Haehling, Doehner, Anker, Banasiak, Cleland, Ponikowski: "Bone marrow iron depletion is common in patients with coronary artery disease." in: International journal of cardiology, Vol. 182, pp. 517-22, (2015) (PubMed).

Łukaszyk, Łukaszyk, Koc-Żórawska, Tobolczyk, Bodzenta-Łukaszyk, Małyszko: "Iron Status and Inflammation in Early Stages of Chronic Kidney Disease." in: Kidney & blood pressure research, Vol. 40, Issue 4, pp. 366-73, (2015) (PubMed).

Young, Huang, Wu, Lai, Hou, Peng, Liang, Lin, Chang, Tsai, Wu, Wu, Ko: "Hemojuvelin modulates iron stress during acute kidney injury: improved by furin inhibitor." in: Antioxidants & redox signaling, Vol. 20, Issue 8, pp. 1181-94, (2014) (PubMed).

Galanopoulos, Raptis, Pramateftakis, Mantzoros, Kanellos, Lazarides: "The effects of iloprost on colonic anastomotic healing in rats under obstructive ileus conditions." in: The Journal of surgical research, Vol. 189, Issue 1, pp. 22-31, (2014) (PubMed).

Synonyme und alternative Namen zu HFE2

hemochromatosis type 2 (juvenile) (HFE2), hemochromatosis type 2 (juvenile) (Hfe2), hemochromatosis type 2 (hfe2), 2310035L15Rik, 5230400G09Rik, AI414844, AI789733, DKFZp468F2322, DL-M, hemojuvelin, HFE2, HFE2A, HJV, hjv, id:ibd3464, JH, RGMC, Rgmc, RGMr, wu:fb38f10, zgc:136698

Bezeichner auf Proteinebene für HFE2

  • RGM domain family member C
  • haemojuvelin
  • hemochromatosis type 2 protein
  • hemojuvelin
  • repulsive guidance molecule c
  • hemochromatosis type 2 (juvenile)
  • hemochromatosis type 2 protein homolog
  • repulsive guidance molecule C
  • hemochromatosis type 2 (juvenile) (human homolog)
  • RGM-like protein
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