HIF1AN Produkte
(Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))
Kategorien
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011].
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Ausgewählte HIF1AN Kategorien
HIF1AN Antikörper
High quality antibodies with extensive validation data.
Empfohlene HIF1AN Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7441979
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IP, IF
Validierungen
- (6)
Kat. Nr.
ABIN527607
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IP, IF
Validierungen
- (5)
Kat. Nr.
ABIN7156025
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene HIF1AN ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956649
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN454393
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1137714
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene HIF1AN Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN935007
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1306622
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7413922
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HIF1AN Produkten
: "Myc-induced nuclear antigen constrains a latent intestinal epithelial cell-intrinsic anthelmintic pathway." in: PLoS ONE, Vol. 14, Issue 2, pp. e0211244, (2019) (PubMed).: "Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1." in: Redox biology, Vol. 26, pp. 101265, (2019) (PubMed).
: "Protein kinase A-dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1." in: Science signaling, Vol. 9, Issue 430, pp. ra56, (2017) (PubMed).
: "miR-148a-3p Mediates Notch Signaling to Promote the Differentiation and M1 Activation of Macrophages." in: Frontiers in immunology, Vol. 8, pp. 1327, (2017) (PubMed).
: "NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells." in: Scientific reports, Vol. 6, pp. 22784, (2016) (PubMed).
: "A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma Has Potent Antitumor Activity." in: Molecular cancer research : MCR, Vol. 14, Issue 3, pp. 253-66, (2016) (PubMed).
: "Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel." in: Journal of cell science, Vol. 128, Issue 2, pp. 225-31, (2015) (PubMed).
: "Factor-inhibiting HIF-1 (FIH-1) is required for human vascular endothelial cell survival." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 7, pp. 2814-27, (2015) (PubMed).
: "Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer." in: BMC cancer, Vol. 13, pp. 526, (2014) (PubMed).
: "Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2)." in: Journal of cell science, Vol. 126, Issue Pt 12, pp. 2629-40, (2013) (PubMed).
Synonyme und alternative Namen zu HIF1AN
hypoxia inducible factor 1 alpha subunit inhibitor (HIF1AN), hypoxia-inducible factor 1, alpha subunit inhibitor (Hif1an), hypoxia inducible factor 1, alpha subunit inhibitor (hif1an), hypoxia-inducible factor 1, alpha subunit inhibitor S homeolog (hif1an.S), hypoxia inducible factor 1 alpha subunit inhibitor (Hif1an), 2310046M24Rik, A830014H24Rik, cb728, FIH1, id:ibd5139Bezeichner auf Proteinebene für HIF1AN
- FIH-1
- factor inhibiting HIF-1
- factor inhibiting HIF1
- hypoxia-inducible factor 1-alpha inhibitor
- hypoxia-inducible factor asparagine hydroxylase
- peptide-aspartate beta-dioxygenase
- hypoxia-inducible factor 1, alpha subunit inhibitor
- LOW QUALITY PROTEIN: hypoxia-inducible factor 1-alpha inhibitor
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