HLA-DRA Produkte
(HLA Class II DR alpha (HLA-DRA))
Kategorien
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008].
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Ausgewählte HLA-DRA Kategorien
HLA-DRA Antikörper
High quality antibodies with extensive validation data.
HLA-DRA ELISA Kits
Reliable ELISA kits for a wide range of species.
HLA-DRA Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene HLA-DRA Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, ELISA, ICC
Validierungen
- (6)
Kat. Nr.
ABIN5542623
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (5)
Kat. Nr.
ABIN6141827
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7437542
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene HLA-DRA ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6974906
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene HLA-DRA Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN5853581
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7401032
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN2129736
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HLA-DRA Produkten
: "Comparison of the biological characteristics of human mesenchymal stem cells derived from exfoliated deciduous teeth, bone marrow, gingival tissue, and umbilical cord." in: Molecular medicine reports, Vol. 18, Issue 6, pp. 4969-4977, (2019) (PubMed).: "Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition." in: The Journal of clinical investigation, Vol. 126, Issue 8, pp. 3130-44, (2016) (PubMed).
: "Characterization and application of two RANK-specific antibodies with different biological activities." in: Immunology letters, Vol. 171, pp. 5-14, (2016) (PubMed).
: "Dermal CD14(+) Dendritic Cell and Macrophage Infection by Dengue Virus Is Stimulated by Interleukin-4." in: The Journal of investigative dermatology, Vol. 135, Issue 7, pp. 1743-51, (2015) (PubMed).
: "Involvement of the TNF-α/TGF-β/IDO axis in IVIg-induced immune tolerance." in: Cytokine, Vol. 71, Issue 2, pp. 181-7, (2015) (PubMed).
: "Ex vivo tetramer staining and cell surface phenotyping for early activation markers CD38 and HLA-DR to enumerate and characterize malaria antigen-specific CD8+ T-cells induced in human volunteers ..." in: Malaria journal, Vol. 12, pp. 376, (2014) (PubMed).
: "Down-regulation of complement receptors on the surface of host monocyte even as in vitro complement pathway blocking interferes in dengue infection." in: PLoS ONE, Vol. 9, Issue 7, pp. e102014, (2014) (PubMed).
: "Vemurafenib enhances MHC induction in BRAF(V600E) homozygous melanoma cells." in: Oncoimmunology, Vol. 2, Issue 1, pp. e22890, (2013) (PubMed).
: "Functional and molecular characterization of ex vivo cultured epiretinal membrane cells from human proliferative diabetic retinopathy." in: BioMed research international, Vol. 2013, pp. 492376, (2013) (PubMed).
: "Efficient differentiation of human pluripotent stem cells into mesenchymal stem cells by modulating intracellular signaling pathways in a feeder/serum-free system." in: Stem cells and development, Vol. 21, Issue 7, pp. 1165-75, (2012) (PubMed).
Synonyme und alternative Namen zu HLA-DRA
major histocompatibility complex, class II, DR alpha L homeolog (hla-dra.L), major histocompatibility complex, class II, DR alpha (HLA-DRA), major histocompatibility complex, class II, DR alpha (MAMU-DRA), major histocompatibility complex, class II, DR alpha (BOLA-DRA), DR-alpha, HLA-DRA, HLA-DRA1, Mamu-DRA1, MLRWBezeichner auf Proteinebene für HLA-DRA
- major histocompatibility complex, class II, DR alpha
- HLA class II histocompatibility antigen, DR alpha chain
- MHC cell surface glycoprotein
- MHC class II antigen DRA
- histocompatibility antigen HLA-DR alpha
- MHC class II DRA
- MHC class II antigen
- BoLA-DR-alpha
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