HLA-DRB3 Produkte
(Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3))
Kategorien
HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB3 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008].
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Ausgewählte HLA-DRB3 Kategorien
HLA-DRB3 Antikörper
High quality antibodies with extensive validation data.
HLA-DRB3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene HLA-DRB3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, FACS
Validierungen
- (4)
Kat. Nr.
ABIN516514
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC
Validierungen
- (3)
Kat. Nr.
ABIN7258926
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (2)
Kat. Nr.
ABIN7155605
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene HLA-DRB3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1306765
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN3092151
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN3114182
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HLA-DRB3 Produkten
: "Cell cycle effects by C-FADD depend on its C-terminal phosphorylation site." in: The Journal of biological chemistry, Vol. 278, Issue 43, pp. 41585-8, (2003) (PubMed).: "A function of Fas-associated death domain protein in cell cycle progression localized to a single amino acid at its C-terminal region." in: Immunity, Vol. 18, Issue 4, pp. 513-21, (2003) (PubMed).
Synonyme und alternative Namen zu HLA-DRB3
major histocompatibility complex, class II, DR beta 3 (HLA-DRB3), major histocompatibility complex, class II, DRB3 (BOLA-DRB3), BLA-DRB3, Bota-DRB01, Bota-DRB02, Bota-DRB04, Bota-DRB07, Bota-DRB21, Bota-DRB22, HLA-DR3B, LA-DRBBezeichner auf Proteinebene für HLA-DRB3
- DR7
- HLA class II histocompatibility antigen, DR beta 3 chain
- HLA class II histocompatibility antigen, DRB1-7 beta chain
- MHC class II HLA-DR beta 3 chain
- MHC class II antigen DR beta 3 chain
- MHC class II antigen DRB3
- human leucocyte antigen DRB3
- BoLA-DRB3.2
- DR beta-chain antigen binding domain
- DR-beta chain MHC class II
- MHC class II DR beta chain
- MHC class II DRB3
- MHC class II antigen BoLA-DRB3
- MHC class II antigen beta chain
- MHC class II leukocyte antigen BoLA-DRB3
- MHC(BoLA) class II DR-beta chain
- histocompatibility complex, class II, DR beta 3
- leukocyte antigen DRB3
- major histocompatibility complex class II DR-beta chain
- major histocompatibility complex, class II, DR beta 3
- major histocompatibility complex, class II, DRB3
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