HMGA2 Produkte
(High Mobility Group AT-Hook 2 (HMGA2))
Kategorien
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Ausgewählte HMGA2 Kategorien
HMGA2 Antikörper
High quality antibodies with extensive validation data.
Empfohlene HMGA2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB
Validierungen
- (3)
Kat. Nr.
ABIN6243228
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN1981306
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IF
Validierungen
- (2)
Kat. Nr.
ABIN6243227
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene HMGA2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7497089
Menge
200 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HMGA2 Produkten
: "MEG3/MIR-376B-3P/HMGA2 axis is involved in pituitary tumor invasiveness." in: Journal of neurosurgery, pp. 1-13, (2020) (PubMed).: "HMGA2 upregulation mediates Cd-induced migration and invasion in A549 cells and in lung tissues of mice." in: Chemico-biological interactions, Vol. 277, pp. 1-7, (2017) (PubMed).
: "Pancreatic cyst fluid concentration of high-mobility group A2 protein acts as a differential biomarker of dysplasia in intraductal papillary mucinous neoplasm." in: Gastrointestinal endoscopy, Vol. 83, Issue 6, pp. 1205-9, (2016) (PubMed).
: "Construction of Conveniently Screening pLKO.1-TRC Vector Tagged with TurboGFP." in: Applied biochemistry and biotechnology, (2016) (PubMed).
: "Histone Deacetylase 10 Regulates the Cell Cycle G2/M Phase Transition via a Novel Let-7-HMGA2-Cyclin A2 Pathway." in: Molecular and cellular biology, Vol. 35, Issue 20, pp. 3547-65, (2015) (PubMed).
: "HMGA2 participates in transformation in human lung cancer." in: Molecular cancer research : MCR, Vol. 6, Issue 5, pp. 743-50, (2008) (PubMed).
: "High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma." in: Molecular cancer, Vol. 6, pp. 5, (2007) (PubMed).
: "Expression and cDNA cloning of human HMGI-C phosphoprotein." in: Biochemical and biophysical research communications, Vol. 201, Issue 1, pp. 63-70, (1994) (PubMed).
Synonyme und alternative Namen zu HMGA2
high mobility group AT-hook 2 (Hmga2), high mobility group AT-hook 2 (hmga2), high mobility group AT-hook 2 (HMGA2), 9430083A20Rik, BABL, HMGI-C, Hmgic, HMGIC, LIPO, pg, pygmy, STQTL9, wu:fc27f12, wu:fc28f02, wu:fc57d12, zgc:77719Bezeichner auf Proteinebene für HMGA2
- high mobility group AT-hook protein 2
- high mobility group protein HMGI-C
- high mobility group protein I
- non-histone chromosomal architectural protein HMGI-C
- high mobility group protein I-C
- likely candidate for the autosomal dwarf locus in the chicken
- High-mobility group protein HMGI-C
- high-mobility group (nonhistone chromosomal) protein isoform I-C
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