HMGCL Produkte
(3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))
Kategorien
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
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Ausgewählte HMGCL Kategorien
HMGCL Antikörper
High quality antibodies with extensive validation data.
HMGCL ELISA Kits
Reliable ELISA kits for a wide range of species.
HMGCL Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene HMGCL Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC (p), ICC, IF
Validierungen
- (5)
Kat. Nr.
ABIN2856650
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
- (3)
Kat. Nr.
ABIN561291
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7155995
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene HMGCL ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1137676
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1137677
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Validierungen
Kat. Nr.
ABIN1137678
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene HMGCL Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN667639
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Baculovirus infected Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN5854983
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1306810
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HMGCL Produkten
: "β-hydroxybutyrate protects hepatocytes against endoplasmic reticulum stress in a sirtuin 1-independent manner." in: Archives of biochemistry and biophysics, Vol. 663, pp. 220-227, (2019) (PubMed).: "The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease." in: Nature medicine, Vol. 21, Issue 3, pp. 263-9, (2015) (PubMed).
: "Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol." in: Journal of lipid research, Vol. 53, Issue 10, pp. 2046-56, (2012) (PubMed).
: "Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 21, pp. 3956-63, (2012) (PubMed).
: "Differential HMG-CoA lyase expression in human tissues provides clues about 3-hydroxy-3-methylglutaric aciduria." in: Journal of inherited metabolic disease, Vol. 33, Issue 4, pp. 405-10, (2010) (PubMed).
Synonyme und alternative Namen zu HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase S homeolog (hmgcl.S), 3-hydroxymethyl-3-methylglutaryl-CoA lyase (HMGCL), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (AFUA_7G01720), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (NFIA_114450), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (ACLA_065820), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (AOR_1_910074), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (PMAA_004600), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (TSTA_103060), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (ARB_04874), 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (TRV_06573), 3-hydroxy-3-methylglutaryl-Coenzyme A lyase (Hmgcl), 3-hydroxymethyl-3-methylglutaryl-CoA lyase (Hmgcl), 3-hydroxymethyl-3-methylglutaryl-CoA lyase (hmgcl), Afu7g01720, AO090038000541, AW476067, HL, zgc:56248Bezeichner auf Proteinebene für HMGCL
- 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase
- 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)
- 3-hydroxy-3-methylglutarate-CoA lyase
- HL
- HMG-CoA lyase
- hydroxymethylglutaryl-CoA lyase, mitochondrial
- 3-hydroxy-3-methylglutaryl-CoA lyase
- hydroxymethylglutaricaciduria
- mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
- 3-hydroxy-3-methylglutaryl-Coenzyme A lyase
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