HNRNPU Produkte
(Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))
Kategorien
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they form complexes with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. Cleavage occurs at the SALD site, resulting in a loss of DNA-binding activity and a concomitant detachment of this protein from nuclear structural sites. But this cleavage does not affect the function of the encoded protein in RNA metabolism. At least two alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte HNRNPU Kategorien
HNRNPU Antikörper
High quality antibodies with extensive validation data.
HNRNPU ELISA Kits
Reliable ELISA kits for a wide range of species.
HNRNPU Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene HNRNPU Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, IF
Validierungen
- (7)
Kat. Nr.
ABIN7101656
Menge
20 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, IF
Validierungen
- (7)
Kat. Nr.
ABIN1680323
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN516594
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene HNRNPU ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967387
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956516
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1743213
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene HNRNPU Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1306883
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7398272
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2722939
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HNRNPU Produkten
: "Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function." in: Cell reports, Vol. 24, Issue 4, pp. 987-1000.e7, (2018) (PubMed).: "A Prader-Willi locus lncRNA cloud modulates diurnal genes and energy expenditure." in: Human molecular genetics, Vol. 22, Issue 21, pp. 4318-28, (2013) (PubMed).
: "The nuclear scaffold protein SAF-A is required for kinetochore-microtubule attachment and contributes to the targeting of Aurora-A to mitotic spindles." in: Journal of cell science, Vol. 124, Issue Pt 3, pp. 394-404, (2011) (PubMed).
: "MicroRNA-binding is required for recruitment of human Argonaute 2 to stress granules and P-bodies." in: Biochemical and biophysical research communications, Vol. 414, Issue 1, pp. 259-64, (2011) (PubMed).
: "In neurons, activity-dependent association of dendritically transported mRNA transcripts with the transacting factor CBF-A is mediated by A2RE/RTS elements." in: Molecular biology of the cell, Vol. 22, Issue 11, pp. 1864-77, (2011) (PubMed).
: "MicroRNA expression profiles of human blood monocyte-derived dendritic cells and macrophages reveal miR-511 as putative positive regulator of Toll-like receptor 4." in: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26487-95, (2011) (PubMed).
: "Preferential repair of oxidized base damage in the transcribed genes of mammalian cells." in: The Journal of biological chemistry, Vol. 286, Issue 8, pp. 6006-16, (2011) (PubMed).
: "Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein." in: The Journal of biological chemistry, Vol. 284, Issue 48, pp. 33384-91, (2009) (PubMed).
: "Involvement of SUMO modification in MBD1- and MCAF1-mediated heterochromatin formation." in: The Journal of biological chemistry, Vol. 281, Issue 32, pp. 23180-90, (2006) (PubMed).
: "Kruppel-like factor 2 transcriptional regulation involves heterogeneous nuclear ribonucleoproteins and acetyltransferases." in: Biochemistry, Vol. 44, Issue 16, pp. 6276-85, (2005) (PubMed).
Synonyme und alternative Namen zu HNRNPU
heterogeneous nuclear ribonucleoprotein U (Hnrnpu), heterogeneous nuclear ribonucleoprotein U (HNRNPU), heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) S homeolog (hnrnpu.S), heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (HNRNPU), AA408410, AI256620, AL024194, AL024437, AW557595, C86794, hnRNP U, Hnrpu, HNRPU, SAF-A, saf-a, SAFA, SN1, Sp120, U21.1Bezeichner auf Proteinebene für HNRNPU
- SAF-A
- heterogenous nuclear ribonucleoprotein U
- nuclear matrix protein sp120
- scaffold attachment factor A
- system N1 Na+ and H+-coupled glutamine transporter
- transporter protein
- transporter protein; system N1 Na+ and H+-coupled glutamine transporter
- heterogeneous nuclear ribonucleoprotein U
- p120 nuclear protein
- pp120
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