HRas proto-oncogene, GTPase Produkte
(HRas proto-oncogene, GTPase (HRAS))
Kategorien
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte HRas proto-oncogene, GTPase Kategorien
HRas proto-oncogene, GTPase Antikörper
High quality antibodies with extensive validation data.
HRas proto-oncogene, GTPase ELISA Kits
Reliable ELISA kits for a wide range of species.
HRas proto-oncogene, GTPase Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene HRas proto-oncogene, GTPase Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IF, IHC (p), ICC
Validierungen
- (4)
- (8)
Kat. Nr.
ABIN2857002
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p)
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN392183
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Dog, Human, Monkey, Mouse, Rat
Applikation
WB, IHC, IF, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN1498713
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene HRas proto-oncogene, GTPase ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967463
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Goat
Analytical Method
Validierungen
Kat. Nr.
ABIN996714
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Dog
Analytical Method
Quantitative
Validierungen
Kat. Nr.
ABIN996715
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene HRas proto-oncogene, GTPase Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1307056
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1307058
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505275
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HRas proto-oncogene, GTPase Produkten
: "Oncogenic RAS-Induced Perinuclear Signaling Complexes Requiring KSR1 Regulate Signal Transmission to Downstream Targets." in: Cancer research, Vol. 78, Issue 4, pp. 891-908, (2019) (PubMed).: "Mouse genetic background influences whether HrasG12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma." in: Oncotarget, Vol. 9, Issue 28, pp. 19753-19766, (2018) (PubMed).
: "Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells." in: Breast cancer research : BCR, Vol. 20, Issue 1, pp. 112, (2018) (PubMed).
: "Oncogenic HrasG12V expression plus knockdown of Cdkn2a using ecotropic lentiviral vectors induces high-grade endometrial stromal sarcoma." in: PLoS ONE, Vol. 12, Issue 10, pp. e0186102, (2017) (PubMed).
: "Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells." in: Molecular cancer therapeutics, Vol. 13, Issue 8, pp. 2073-80, (2014) (PubMed).
: "Mutational analysis of HRAS and KRAS genes in oral carcinoma cell lines." in: Odontology / the Society of the Nippon Dental University, Vol. 100, Issue 2, pp. 149-55, (2012) (PubMed).
: "Postzygotic HRAS and KRAS mutations cause nevus sebaceous and Schimmelpenning syndrome." in: Nature genetics, Vol. 44, Issue 7, pp. 783-7, (2012) (PubMed).
: "p66(Shc) restrains Ras hyperactivation and suppresses metastatic behavior." in: Oncogene, Vol. 29, Issue 41, pp. 5559-67, (2010) (PubMed).
: "The Hsp90 molecular chaperone: an open and shut case for treatment." in: The Biochemical journal, Vol. 410, Issue 3, pp. 439-53, (2008) (PubMed).
: "Expressed as the sole Hsp90 of yeast, the alpha and beta isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90beta generates ..." in: The FEBS journal, Vol. 274, Issue 17, pp. 4453-63, (2007) (PubMed).
Synonyme und alternative Namen zu HRas proto-oncogene, GTPase
HRas proto-oncogene, GTPase (HRAS), v-Ha-ras Harvey rat sarcoma viral oncogene homolog a (hrasa), neuroblastoma RAS viral (v-ras) oncogene homolog pseudogene (LOC733587), HRas proto-oncogene, GTPase (Hras), Harvey rat sarcoma viral oncogene homolog L homeolog (hras.L), Harvey rat sarcoma viral oncogene homolog (hras), Harvey rat sarcoma virus oncogene (Hras), NRAS proto-oncogene, GTPase (NRAS), -Ha-ras Harvey rat sarcoma viral oncogene homolog b (hrasb), C-BAS/HAS, c-bas/has, C-H-RAS, c-H-ras, c-Ha-ras, C-HA-RAS1, c-rasHa, CTLO, H-RAS, H-Ras, H-ras, H-RASIDX, Ha-ras, HAMSV, Harvey-ras, hras, HRAS, Hras-1, HRAS1, hras1, hrasl, K-RAS, K-Ras, Kras2, N-RAS, N-Ras, ras, RASH1, rash1, zgc:110250, zgc:110734Bezeichner auf Proteinebene für HRas proto-oncogene, GTPase
- GTP- and GDP-binding peptide B
- GTPase HRas
- H-Ras-1
- Ha-Ras1 proto-oncoprotein
- Ras family small GTP binding protein H-Ras
- c-has/bas p21 protein
- c-ras-Ki-2 activated oncogene
- p19 H-RasIDX protein
- p21ras
- transformation gene: oncogene HAMSV
- transforming protein p21
- v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- xRAS1
- Transforming protein p21
- neuroblastoma ras oncogene
- c-H-ras
- v-Ha-ras Harvey rat sarcoma viral oncogene-like protein
- Harvey ras1 protein
- Harvey rat sarcoma viral (v-Ha-ras) oncogene homolog
- ras p21
- small G-protein H-Ras
- GTPase HRas (Transforming protein p21) (H-Ras-1) (c-H-ras)
- Harvey ras 1
- H-ras 1 protein
- c-Ha-ras p21 protein
- c-Ha-ras transgene
- transforming protein P21
- GTPase NRas
- transforming protein N-Ras
- -Ha-ras Harvey rat sarcoma viral oncogene homolog b
- -Ha-ras Harvey rat sarcoma viral oncogene homolog, like
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