HSD11B2 Produkte
(Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
Kategorien
There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development. Mutations in this gene cause the syndrome of apparent mineralocorticoid excess and hypertension. [provided by RefSeq, Feb 2010].
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Ausgewählte HSD11B2 Kategorien
HSD11B2 Antikörper
High quality antibodies with extensive validation data.
HSD11B2 ELISA Kits
Reliable ELISA kits for a wide range of species.
HSD11B2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene HSD11B2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Horse, Mouse, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (4)
- (7)
Kat. Nr.
ABIN701680
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, IHC
Validierungen
- (4)
Kat. Nr.
ABIN7264121
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN653721
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene HSD11B2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6956636
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956637
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative
Validierungen
- (1)
Kat. Nr.
ABIN1049562
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene HSD11B2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1307105
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1307107
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7407292
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HSD11B2 Produkten
: "A novel derivatives of thiazol-4(5H)-one and their activity in the inhibition of 11β-hydroxysteroid dehydrogenase type 1." in: Bioorganic chemistry, Vol. 79, pp. 115-121, (2019) (PubMed).: "Prenatal maternal distress affects atopic dermatitis in offspring mediated by oxidative stress." in: The Journal of allergy and clinical immunology, Vol. 138, Issue 2, pp. 468-475.e5, (2016) (PubMed).
: "Regulation of glucocorticoid-related genes and receptors/regulatory enzyme expression in intrauterine growth restriction filial rats." in: Life sciences, Vol. 150, pp. 61-6, (2016) (PubMed).
: "Preeclampsia induced by cadmium in rats is related to abnormal local glucocorticoid synthesis in placenta." in: Reproductive biology and endocrinology : RB&E, Vol. 12, pp. 77, (2015) (PubMed).
: "Preeclampsia is associated with a deficiency of lipoxin A4, an endogenous anti-inflammatory mediator." in: Fertility and sterility, Vol. 102, Issue 1, pp. 282-290.e4, (2014) (PubMed).
Synonyme und alternative Namen zu HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2 L homeolog (hsd11b2.L), hydroxysteroid 11-beta dehydrogenase 2 (HSD11B2), hydroxysteroid 11-beta dehydrogenase 2 (Hsd11b2), 11-HSD2, 11HSD2, AME, AME1, HSD2, HSD11B2, HSD11K, MGC81883, SDR9C3Bezeichner auf Proteinebene für HSD11B2
- hydroxysteroid (11-beta) dehydrogenase 2
- corticosteroid 11-beta-dehydrogenase isozyme 2
- 11 beta-hydroxysteroid dehydrogenase type 2
- -HSD11 type II
- 11-DH2
- 11-beta-HSD2
- 11-beta-hydroxysteroid dehydrogenase type 2
- 11-beta-hydroxysteroid dehydrogenase type II
- NAD-dependent 11-beta-hydroxysteroid dehydrogenase
- short chain dehydrogenase/reductase family 9C member 3
- 11-beta hydroxysteroid dehydrogenase
- hydroxysteroid 11-beta dehydrogenase 2
- 11-beta-hydroxysteroid dehydrogenase 2
- 11(beta)-HSD2
- Hydroxysteroid dehydrogenase, 11 beta type 2
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