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HSD17B10 Produkte

(Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Kategorien

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008].

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Ausgewählte HSD17B10 Kategorien

HSD17B10 Antikörper

High quality antibodies with extensive validation data.

HSD17B10 ELISA Kits

Reliable ELISA kits for a wide range of species.

HSD17B10 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene HSD17B10 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), ICC, IHC (wm)
Validierungen
  • (8)
Kat. Nr. ABIN2854703
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Monkey
Applikation WB, IHC, IF, IHC (p), FACS
Validierungen
  • (7)
Kat. Nr. ABIN1498724
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (7)
Kat. Nr. ABIN3042460
Menge 100 μg
Datenblatt Datenblatt

Empfohlene HSD17B10 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6967495
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6975066
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956639
Menge 96 tests
Datenblatt Datenblatt

Empfohlene HSD17B10 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7490903
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123386
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN666970
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren HSD17B10 Produkten

Kristofiková, Bocková, Hegnerová, Bartos, Klaschka, Rícný, Rípová, Homola: "Enhanced levels of mitochondrial enzyme 17beta-hydroxysteroid dehydrogenase type 10 in patients with Alzheimer disease and multiple sclerosis." in: Molecular bioSystems, Vol. 5, Issue 10, pp. 1174-9, (2009) (PubMed).

Tilton, Haidacher, Lejeune, Zhang, Zhao, Kurosky, Brasier, Denner: "Diabetes-induced changes in the renal cortical proteome assessed with two-dimensional gel electrophoresis and mass spectrometry." in: Proteomics, Vol. 7, Issue 10, pp. 1729-42, (2007) (PubMed).

Takuma, Yao, Huang, Xu, Chen, Luddy, Trillat, Stern, Arancio, Yan: "ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 19, Issue 6, pp. 597-8, (2005) (PubMed).

Lustbader, Cirilli, Lin, Xu, Takuma, Wang, Caspersen, Chen, Pollak, Chaney, Trinchese, Liu, Gunn-Moore, Lue, Walker, Kuppusamy, Zewier, Arancio, Stern, Yan, Wu: "ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease." in: Science (New York, N.Y.), Vol. 304, Issue 5669, pp. 448-52, (2004) (PubMed).

Kissinger, Rejto, Pelletier, Thomson, Showalter, Abreo, Agree, Margosiak, Meng, Aust, Vanderpool, Li, Tempczyk-Russell, Villafranca: "Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics." in: Journal of molecular biology, Vol. 342, Issue 3, pp. 943-52, (2004) (PubMed).

He, Merz, Yang, Pullakart, Mehta, Schulz, Yang: "Function of human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase in androgen metabolism." in: Biochimica et biophysica acta, Vol. 1484, Issue 2-3, pp. 267-77, (2000) (PubMed).

He, Schulz, Yang: "A human brain L-3-hydroxyacyl-coenzyme A dehydrogenase is identical to an amyloid beta-peptide-binding protein involved in Alzheimer's disease." in: The Journal of biological chemistry, Vol. 273, Issue 17, pp. 10741-6, (1998) (PubMed).

Synonyme und alternative Namen zu HSD17B10

hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), hydroxysteroid (17-beta) dehydrogenase 10 (hsd17b10), hydroxysteroid 17-beta dehydrogenase 10 (HSD17B10), hydroxysteroid (17-beta) dehydrogenase 10 L homeolog (hsd17b10.L), hydroxysteroid (17-beta) dehydrogenase 10 (Hsd17b10), 17b-HSD10, 17bHSD10, abad, ABAD, Ads9, camr, CAMR, DUPXp11.22, erab, ERAB, hadh2, HADH2, Hadh2, hcd2, HCD2, hsd10, HSD17B10, im:6899159, mhbd, MHBD, mrpp2, MRPP2, mrx17, MRX17, mrx31, MRX31, mrxs10, MRXS10, schad, SCHAD, sdr5c1, SDR5C1, wu:fj61f03, zgc:101605

Bezeichner auf Proteinebene für HSD17B10

  • hydroxysteroid (17-beta) dehydrogenase 10
  • 3-hydroxyacyl-CoA dehydrogenase type-2
  • hydroxyacyl-Coenzyme A dehydrogenase, type II
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
  • AB-binding alcohol dehydrogenase
  • amyloid-beta peptide binding alcohol dehydrogenase
  • endoplasmic reticulum-associated amyloid beta-peptide-binding protein
  • mitochondrial RNase P subunit 2
  • mitochondrial ribonuclease P protein 2
  • short chain L-3-hydroxyacyl-CoA dehydrogenase type 2
  • short chain dehydrogenase/reductase family 5C, member 1
  • short chain type dehydrogenase/reductase XH98G2
  • 17-beta-HSD 10
  • 17-beta-hydroxysteroid dehydrogenase 10
  • 3-hydroxyacyl-CoA dehydrogenase type II
  • hydroxyacyl-Coenzyme A dehydrogenase type II
  • mitochondrial RNase P protein 2
  • type II HADH
  • amyloid beta-peptide binding protein
  • short chain L-3-hydroxyacyl-CoA dehydrogenase
  • hydroxyacyl-Coenzyme A dehydrogenase, type II hydroxyacyl-Coenzyme A
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