IDH1 Produkte
(Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
Kategorien
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. [provided by RefSeq, Jul 2008].
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Ausgewählte IDH1 Kategorien
IDH1 Antikörper
High quality antibodies with extensive validation data.
IDH1 ELISA Kits
Reliable ELISA kits for a wide range of species.
IDH1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene IDH1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (1)
- (8)
Kat. Nr.
ABIN3023106
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (10)
Kat. Nr.
ABIN7436579
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, FACS, IF, IHC (p)
Validierungen
- (7)
Kat. Nr.
ABIN391660
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene IDH1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (4)
- (2)
Kat. Nr.
ABIN6574327
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957223
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN581788
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene IDH1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (2)
Kat. Nr.
ABIN7274843
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123639
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123640
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren IDH1 Produkten
: "Serological Biomarkers for Early Detection of Hepatocellular Carcinoma: A Focus on Autoantibodies against Tumor-Associated Antigens Encoded by Cancer Driver Genes." in: Cancers, Vol. 12, Issue 5, (2020) (PubMed).: "IDH2 is a novel diagnostic and prognostic serum biomarker for non-small-cell lung cancer." in: Molecular oncology, Vol. 12, Issue 5, pp. 602-610, (2019) (PubMed).
: "lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma." in: International journal of oncology, Vol. 53, Issue 2, pp. 551-566, (2018) (PubMed).
: "AMP-Activated Protein Kinase α2 in Neutrophils Regulates Vascular Repair via Hypoxia-Inducible Factor-1α and a Network of Proteins Affecting Metabolism and Apoptosis." in: Circulation research, Vol. 120, Issue 1, pp. 99-109, (2016) (PubMed).
: "Identification of proteins responsible for adriamycin resistance in breast cancer cells using proteomics analysis." in: Scientific reports, Vol. 5, pp. 9301, (2016) (PubMed).
: "DIGE based proteome analysis of mammary gland tissue in water buffalo (Bubalus bubalis): Lactating vis-a-vis heifer." in: Journal of proteomics, Vol. 119C, pp. 100-111, (2015) (PubMed).
: "The effects of PGC-1α on the proliferation and energy metabolism of malignant endometrial cancer cells." in: OncoTargets and therapy, Vol. 8, pp. 769-74, (2015) (PubMed).
: "Effective immuno-targeting of the IDH1 mutation R132H in a murine model of intracranial glioma." in: Acta neuropathologica communications, Vol. 3, pp. 4, (2015) (PubMed).
: "A high-throughput fluorimetric assay for 2-hydroxyglutarate identifies Zaprinast as a glutaminase inhibitor." in: Cancer discovery, Vol. 4, Issue 7, pp. 828-39, (2014) (PubMed).
: "IDH1 regulates phospholipid metabolism in developing astrocytes." in: Neuroscience letters, Vol. 582, pp. 87-92, (2014) (PubMed).
Synonyme und alternative Namen zu IDH1
isocitrate dehydrogenase (NADP(+)) 1, cytosolic (IDH1), isocitrate dehydrogenase 1 (NADP+), soluble (Idh1), isocitrate dehydrogenase (NADP(+)) 1, cytosolic (Idh1), isocitrate dehydrogenase 1 (NADP+) L homeolog (idh1.L), isocitrate dehydrogenase 1 (NADP+), soluble (idh1), isocitrate dehydrogenase 1 (IDH1), AI314845, AI788952, cb876, E030024J03Rik, F23E12.180, F23E12_180, fm90e09, Id-1, IDCD, IDH, Idh-1, IDH-I, IDP, IDPC, Idpc, im:7143416, isocitrate dehydrogenase 1, isocitrate dehydrogenase I, NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 1, NADP-CICDH, PICD, wu:fm90e09Bezeichner auf Proteinebene für IDH1
- NADP(+)-specific ICDH
- NADP-dependent isocitrate dehydrogenase, cytosolic
- NADP-dependent isocitrate dehydrogenase, peroxisomal
- isocitrate dehydrogenase [NADP] cytoplasmic
- oxalosuccinate decarboxylase
- IDH
- IDP
- cytosolic NADP-isocitrate dehydrogenase
- isocitrate dehydrogenase 1 (NADP+), soluble
- isocitrate dehydrogenase [NADP] cytoplasmic-like
- Isocitrate dehydrogenase 1, soluble
- isocitrate dehydrogenase 1
- IDH-I
- Isocitric dehydrogenase 1
- NAD(+)-specific ICDH 1
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