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IDH3A Produkte

(Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

Kategorien

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008].

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Ausgewählte IDH3A Kategorien

IDH3A Antikörper

High quality antibodies with extensive validation data.

IDH3A ELISA Kits

Reliable ELISA kits for a wide range of species.

IDH3A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene IDH3A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, IF
Validierungen
  • (8)
Kat. Nr. ABIN7258018
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (7)
Kat. Nr. ABIN7268029
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), ICC
Validierungen
  • (5)
Kat. Nr. ABIN2855763
Menge 100 μL
Datenblatt Datenblatt

Empfohlene IDH3A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6205396
Menge 96 tests
Datenblatt Datenblatt

Empfohlene IDH3A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1307374
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2723870
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Pig
Source Yeast
Validierungen
Kat. Nr. ABIN1472581
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren IDH3A Produkten

Zhang, Wang, Shi, Liu, Sun, Hou, Zhang, Zhao, Zhou, Mi: "Metabolic reprogramming of cancer-associated fibroblasts by IDH3? downregulation." in: Cell reports, Vol. 10, Issue 8, pp. 1335-48, (2015) (PubMed).

Xing, Yuan, Xu, Gu, Liang, Lu: "Proteomic identification of mitochondrial targets involved in andrographolide sodium bisulfite-induced nephrotoxicity in a rat model." in: Environmental toxicology and pharmacology, Vol. 40, Issue 2, pp. 592-9, (2015) (PubMed).

Lin, Cheng, Tsai, Tsai, Hu, Chang, Yeh, Chen, Liao, Chang: "Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy." in: Scientific reports, Vol. 2, pp. 785, (2012) (PubMed).

Soundar, Park, Huh, Colman: "Evaluation by mutagenesis of the importance of 3 arginines in alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase." in: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52146-53, (2003) (PubMed).

Kim, Koh, Kim, Jo, Huh, Jeong, Lee, Song, Huh: "Identification and functional characterization of a novel, tissue-specific NAD(+)-dependent isocitrate dehydrogenase beta subunit isoform." in: The Journal of biological chemistry, Vol. 274, Issue 52, pp. 36866-75, (2000) (PubMed).

Weiss, Zeng, Huang, Sobocka, Rushbrook: "Bovine NAD+-dependent isocitrate dehydrogenase: alternative splicing and tissue-dependent expression of subunit 1." in: Biochemistry, Vol. 39, Issue 7, pp. 1807-16, (2000) (PubMed).

Synonyme und alternative Namen zu IDH3A

isocitrate dehydrogenase 3 (NAD+) alpha (idh3a), isocitrate dehydrogenase 3 (NAD(+)) alpha (IDH3A), isocitrate dehydrogenase 3 (NAD(+)) alpha (idh3a), isocitrate dehydrogenase 3 (NAD+) alpha S homeolog (idh3a.S), isocitrate dehydrogenase 3 (NAD+) alpha (Idh3a), 1110003P10Rik, 1500012E04Rik, AA407078, AI316514, BG1, idh3a, IDH3A, MGC76128, zgc:56380, zgc:85631

Bezeichner auf Proteinebene für IDH3A

  • isocitrate dehydrogenase 3 (NAD+) alpha
  • isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
  • mitochondrial isocitrate dehydrogenase (nad) subunit alpha
  • H-IDH alpha
  • NAD(+)-specific ICDH subunit alpha
  • NAD(H)-specific isocitrate dehydrogenase alpha subunit
  • NAD+-specific ICDH
  • isocitrate dehydrogenase (NAD+) alpha chain
  • isocitric dehydrogenase subunit alpha
  • isocitrate dehydrogenase subunits 3/4
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