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IGF2R Produkte

(Insulin-Like Growth Factor 2 Receptor (IGF2R))
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele. [provided by RefSeq, Apr 2013].

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Ausgewählte IGF2R Kategorien

IGF2R Antikörper

High quality antibodies with extensive validation data.

IGF2R ELISA Kits

Reliable ELISA kits for a wide range of species.

IGF2R Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene IGF2R Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Non-Human Primate
Applikation WB, FACS, IP
Validierungen
  • (2)
  • (4)
Kat. Nr. ABIN94039
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (5)
Kat. Nr. ABIN7267905
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN5693085
Menge 100 μg
Datenblatt Datenblatt

Empfohlene IGF2R ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6967650
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956801
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN2703119
Menge 96 tests
Datenblatt Datenblatt

Empfohlene IGF2R Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123457
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1307559
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN1046788
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren IGF2R Produkten

Gerber, Mosser, Boury-Jamot, Stumpe, Piersigilli, Goepfert, Dengjel, Albrecht, Magara, Fraering: "The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease." in: Acta neuropathologica communications, Vol. 7, Issue 1, pp. 13, (2019) (PubMed).

Godoy-Parejo, Deng, Liu, Chen: "Insulin Stimulates PI3K/AKT and Cell Adhesion to Promote the Survival of Individualized Human Embryonic Stem Cells." in: Stem cells (Dayton, Ohio), Vol. 37, Issue 8, pp. 1030-1041, (2019) (PubMed).

Kakegawa, Katoh, Narumi, Miura, Motohashi, Takahashi, Kohda, Fukazawa, Yuzaki, Matsuda: "Optogenetic Control of Synaptic AMPA Receptor Endocytosis Reveals Roles of LTD in Motor Learning." in: Neuron, Vol. 99, Issue 5, pp. 985-998.e6, (2018) (PubMed).

Mu, Zhang, Wang, Xu, Ahmed, Pang, Chibbar, Freywald, Huang, Zhu, Xiang: "Enhanced suppression of polyclonal CD8+25+regulatory T cells via exosomal arming of antigen-specific peptide/MHC complexes." in: Journal of leukocyte biology, Vol. 101, Issue 5, pp. 1221-1231, (2017) (PubMed).

Ahmed, Xiang: "mTORC1 regulates mannose-6-phosphate receptor transport and T-cell vulnerability to regulatory T cells by controlling kinesin KIF13A." in: Cell discovery, Vol. 3, pp. 17011, (2017) (PubMed).

Liu, Yu, Wu, Sun, Su, You, Xin: "CD44+fibroblasts increases breast cancer cell survival and drug resistance via IGF2BP3-CD44-IGF2 signalling." in: Journal of cellular and molecular medicine, Vol. 21, Issue 9, pp. 1979-1988, (2017) (PubMed).

Martín-Montañez, Millon, Boraldi, Garcia-Guirado, Pedraza, Lara, Santin, Pavia, Garcia-Fernandez: "IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids." in: Redox biology, Vol. 13, pp. 69-81, (2017) (PubMed).

Takahashi, Mashima, Miura, Maeda, Goto, Goto, Sun-Wada, Wada, Ohnishi: "Disruption of Small GTPase Rab7 Exacerbates the Severity of Acute Pancreatitis in Experimental Mouse Models." in: Scientific reports, Vol. 7, Issue 1, pp. 2817, (2017) (PubMed).

Chanprasertyothin, Jongjaroenprasert, Ongphiphadhanakul: "The association of soluble IGF2R and IGF2R gene polymorphism with type 2 diabetes." in: Journal of diabetes research, Vol. 2015, pp. 216383, (2015) (PubMed).

Schatzlmaier, Supper, Göschl, Zwirzitz, Eckerstorfer, Ellmeier, Huppa, Stockinger: "Rapid multiplex analysis of lipid raft components with single-cell resolution." in: Science signaling, Vol. 8, Issue 395, pp. rs11, (2015) (PubMed).

Synonyme und alternative Namen zu IGF2R

insulin like growth factor 2 receptor (IGF2R), insulin-like growth factor 2 receptor (Igf2r), insulin like growth factor 2 receptor (igf2r), AI661837, CD222, cd222, CI-MPR, CIMPR, cimpr, M6P-R, m6p-r, M6P/IGF2R, MPR1, Mpr300, MPRI, mpri

Bezeichner auf Proteinebene für IGF2R

  • 300 kDa mannose 6-phosphate receptor
  • CI Man-6-P receptor
  • CI-MPR
  • IGF-II receptor
  • M6P/IGF2 receptor
  • M6P/IGF2R
  • M6PR
  • MPR 300
  • cation-independent mannose-6 phosphate receptor
  • cation-independent mannose-6-phosphate receptor
  • insulin-like growth factor II receptor
  • IGF-II/CI-MPR
  • cation-independent MPR
  • cation-independent mannose 6-phosphate receptor
  • mannose-6-phosphate receptor, cation independent
  • insulin-like growth factor receptor type 2
  • cation-independent mannose 6 phosphate receptor
  • insulin-like growth factor 2 receptor
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